Results 331 to 340 of about 1,679,247 (398)

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

open access: yesMovement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori   +15 more
wiley   +1 more source

Frequency and implications of malnutrition in systemic sclerosis. [PDF]

open access: yesRheumatology (Oxford)
Fairley JL   +11 more
europepmc   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

Global Disease Burden of Immune‐Mediated Inflammatory Diseases (IMIDs), 1990–2021

open access: yesMed Research, EarlyView.
This study provides the first standardized evaluation of the direct health burden of inflammatory and immune‐mediated diseases (IMIDs) across 231 locations worldwide from 1990 to 2021, spanning five geographic levels: global, SDI regions, GBD regions, countries, and territories.
Xueping Zhu   +7 more
wiley   +1 more source

Malignancy-associated risk factors in patients with systemic sclerosis. [PDF]

open access: yesJ Scleroderma Relat Disord
Baysal S   +7 more
europepmc   +1 more source

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