Results 271 to 280 of about 13,108,811 (339)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Systems analysis and improvement approach to optimize tuberculosis (SAIA-TB) screening, treatment, and prevention in South Africa: a stepped-wedge cluster randomized trial. [PDF]

Implement Sci Commun
van de Water BJ, Brooks MB, Matji R, Ncanywa B, Dikgale F, Abuelezam NN, Mzileni B, Nokwe M, Moko S, Mvusi L, Loveday M, Gimbel S.   +11 more
europepmc   +1 more source

The invisible work of nursing assistants in nursing homes : an analysis of the ethical dimension of workload and the uses of an AI System through activity analysis

Yann Le Chêne
openalex   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Adoption of C-reactive protein rapid tests for the management of acute childhood infections in hospitals in the Netherlands and England: a comparative health systems analysis. [PDF]

BMC Health Serv Res
Dewez JE, Nijman RG, Fitchett EJA, Li EC, Luu QF, Lynch R, Emonts M, de Groot R, van der Flier M, Philipsen R, Ettelt S, Yeung S.   +11 more
europepmc   +1 more source

Stability analysis of infinite dimensional systems and effect of perturbations/ : theory and applications

Dagbégnon Loko
openalex   +1 more source

Stabilizing time-lagged climate impacts requires net-negative emissions for centuries

Environmental Research Letters
Johannes Bednar, Artem Baklanov, Justin Macinante, Jim W Hall, Thomas Gasser, Michael Obersteiner   +5 more
doaj   +1 more source

A dynamical systems analysis of change in PTSD symptoms, depression symptoms, and suicidal ideation among military personnel during treatment for PTSD. [PDF]

J Affect Disord
Bryan CJ, Butner JE, Tabares JV, Brown LA, Young-McCaughan S, Hale WJ, Litz BT, Yarvis JS, Fina BA, Foa EB, Resick PA, Peterson AL, STRONG STAR Consortium.   +12 more
europepmc   +1 more source

Domestic abuse, primary care and child mental health services: A systems analysis of service coordination from professionals’ perspectives

Powell C, Adisa O, Herlitz L, Bains S, Eyrúnardóttir Clark S, Deighton J, Syed S, Gilbert R, Feder G, Howarth E.   +9 more
europepmc   +1 more source

Work Systems Analysis of Emergency Nurse Patient Flow Management Using the Systems Engineering Initiative for Patient Safety Model: Applying Findings From a Grounded Theory Study.

JMIR Hum Factors
Benjamin E, Giuliano KK.
europepmc   +1 more source