Results 41 to 50 of about 3,795,802 (269)

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Practice and perspectives in the validation of resource management models

Nature Communications, 2018
Credibility of long-term projection in quantitative models is continuously under debate and they rely on validation to prove projection accuracy. Here the authors investigated the views on the validation approaches and they show that empirical data plays
Sibel Eker, Elena Rovenskaya, Michael Obersteiner, Simon Langan   +3 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

A taxonomy-based understanding of community flood resilience

Ecology and Society
Reducing disaster risk and enhancing resilience are major global societal challenges. To inform this challenge, understanding resilience at the community level is especially important because the impact of disasters and the potential for resilient ...
Dipesh Chapagain, Stefan Hochrainer-Stigler, Stefan Velev, Adriana Keating, Jung Hee Hyun, Naomi Rubenstein, Reinhard Mechler   +6 more
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Positive Externalities in the Polycrisis: Effectively Addressing Disaster and Climate Risks for Generating Multiple Resilience Dividends

International Journal of Disaster Risk Science
With multiple risks interacting and shocks proliferating across geographies and sectors, the concept of polycrisis has come to the fore. Polycrisis describes interwoven and overlapping crises that cannot be understood or resolved in isolation.
Reinhard Mechler, Piotr Żebrowski, Romain Clercq-Roques, Pratik Patil, Stefan Hochrainer-Stigler   +4 more
doaj   +1 more source

Reflections on the large-scale application of a community resilience measurement framework across the globe

Climate Services
This paper reflects on learnings and analysis from an extensively globally applied, standardized community disaster resilience measurement framework that utilises bottom-up (locally collected) data. These lessons, from over a decade of on-the-ground work
Adriana Keating, Stefan Hochrainer-Stigler, Reinhard Mechler, Finn Laurien, Naomi Rubenstein, Teresa Deubelli, Stefan Velev, Michael Szoenyi, David Nash   +8 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

A cross-country comparison of math achievement at teen age and cognitive performance 40 years later

Demographic Research, 2014
Background: Maintaining cognitive functioning through mid- to late-life is relevant for the individual and societal aim of active ageing. Evidence shows considerable stability in individual-level rank-ordering of cognitive functioning, but little ...
Vegard Skirbekk, Valeria Bordone, Daniela Weber   +2 more
doaj   +1 more source