Results 91 to 100 of about 20,790,490 (298)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A national approach to systems integration of large complex systems

, 2004
Large-scale systems, such as rail networks, air traffic control systems, and networked defence systems are vital to national well-being. However, modern systems are becoming increasingly complex in nature and their development is proving problematical ...
Nandagopal, D., Cook, S., Bates, B., Allison, S., Sciacca, L., Shackleton, D.   +5 more
core  

A molecular approach to complex adaptive systems [PDF]

, 2007
Complex Adaptive Systems (CAS) are dynamical networks of interacting agents which as a whole determine the behavior, adaptivity and cognitive ability of the system. CAS are ubiquitous and occur in a variety of natural and artificial systems (e.g., cells,
McMullin, Barry, Decraene, James, Mitchell, George G.   +2 more
core   +2 more sources

МОДЕЛЬНЕ ПОДАННЯ ФУНКЦІОНУВАННЯ ДОСЛІДЖУВАНИХ СИСТЕМ

Інформаційні технології і засоби навчання, 2010
Наведені тлумачення термінів методи і способи, механізми і технології функціонування систем, запропоновані їх означення, описана їх взаємозалежність і взаємообумовленість з позицій системного і задачного підходів.
Valeriy Yu. Bykov
doaj  

The spacetime of regional economic systems: Methodology, history, potential

Journal of New Economy
Implementing time and space into the conceptual framework of economic theory and regional economics is a relevant direction of research. The article particularly focuses on the issue of how the space-time continuum of economic systems is formed ...
Evgeny P. Dyatel
doaj   +1 more source

Systems Approach Conception of Legal Regulation

Law: Journal of the University of Latvia, 2018
The article is devoted to the problem of the formation of systems approach conception of legal regulation in the context of integrative jurisprudence. Today the mechanistic approach to legal regulation retains its popularity.
Maria A. Kapustina
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

InterQnet: A Heterogeneous Full-Stack Approach to Co-Designing Scalable Quantum Networks

IEEE Transactions on Quantum Engineering
Quantum communications have progressed significantly, moving from a theoretical concept to small-scale experiments to recent metropolitan-scale demonstrations.
Joaquin Chung, Daniel Dilley, Ely Eastman, Alvin Gonzales, Kara Hokenstad, Md Shariful Islam, Varun Jorapur, Joseph Petrullo, Andy C. Y. Li, Bikun Li, Vasileios Niaouris, Anirudh Ramesh, Ansh Singal, Zeyu Ye, Caitao Zhan, Michael Bishof, Eric Chitambar, Jacob P. Covey, Alan Dibos, Xu Han, Liang Jiang, Prem Kumar, Jeffrey Larson, Zain H. Saleem, Rajkumar Kettimuthu   +24 more
doaj   +1 more source

Establishing and implementing best practice to reduce unplanned admissions in those aged 85 years and over through system change [Establishing System Change for Admissions of People 85+ (ESCAPE 85+)]: a mixed-methods case study approach

Health Services and Delivery Research, 2015
Background: In England, between 2007/8 and 2009/10, the rate of unplanned hospital admissions of people aged 85 years and above rose from 48 to 52 per 100. There was substantial variation, with some areas showing a much faster rate of increase and others
Andrew Wilson, Richard Baker, John Bankart, Jay Banerjee, Ran Bhamra, Simon Conroy, Stoyan Kurtev, Kay Phelps, Emma Regen, Stephen Rogers, Justin Waring   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source