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Current Opinion in Biotechnology, 2011
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Kishony, Roy, Hatzimanikatis, Vassily
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Kishony, Roy, Hatzimanikatis, Vassily
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Systems Biology and the Biology of Systems
Physiology, 2010When I sit down to write an editorial for Physiology, I flatter myself that the two or three people who will ultimately read it want to hear my thoughts on a “big” topic. It strikes me that, within the rarefied realm of academic biology, there few bigger topics, or at least few topics more ...
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Introduction to systems biology [PDF]
, 2007 The developments in the molecular biosciences have made possible a shift to combined molecular and system-level approaches to biological research under the name of Systems Biology. It integrates many types of molecular knowledge, which can best be achieved by the synergistic use of models and experimental data.
Hans V. Westerhoff +5 more
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The Systems Biology of Glycosylation [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Andre Levchenko +2 more
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The evolution of molecular biology into systems biology
Nature Biotechnology, 2004Systems analysis has historically been performed in many areas of biology, including ecology, developmental biology and immunology. More recently, the genomics revolution has catapulted molecular biology into the realm of systems biology. In unicellular organisms and well-defined cell lines of higher organisms, systems approaches are making definitive ...
Hans V. Westerhoff, Bernhard O. Palsson
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Trends in Microbiology, 2007
The advent of functional genomics has enabled the molecular biosciences to come a long way towards characterizing the molecular constituents of life. Yet, the challenge for biology overall is to understand how organisms function. By discovering how function arises in dynamic interactions, systems biology addresses the missing links between molecules ...
Hans V. Westerhoff +2 more
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The advent of functional genomics has enabled the molecular biosciences to come a long way towards characterizing the molecular constituents of life. Yet, the challenge for biology overall is to understand how organisms function. By discovering how function arises in dynamic interactions, systems biology addresses the missing links between molecules ...
Hans V. Westerhoff +2 more
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Communications of the ACM, 2009
The convergence of CS and biology will serve both disciplines, providing each with greater power and relevance.
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The convergence of CS and biology will serve both disciplines, providing each with greater power and relevance.
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Systems biology of antioxidants
Clinical Science, 2012Understanding the role of oxidative injury will allow for therapy with agents that scavenge ROS (reactive oxygen species) and antioxidants in the management of several diseases related to free radical damage. The majority of free radicals are generated by mitochondria as a consequence of the mitochondrial cycle, whereas free radical accumulation is ...
Andriantsitohaina, Ramaroson +10 more
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Metabolomics in Systems Biology
Annual Review of Plant Biology, 2003The primary aim of “omic” technologies is the nontargeted identification of all gene products (transcripts, proteins, and metabolites) present in a specific biological sample. By their nature, these technologies reveal unexpected properties of biological systems.
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Current Opinion in Biotechnology, 2010
In his editorial overview for the 2008 Special Issue on this topic, the late Jaroslav Stark pointedly noted that systems biology is no longer a niche pursuit, but a recognized discipline in its own right “noisily” coming of age [1]. Whilst general underlying principles and basic techniques are now reasonably well established, we see a progressive shift
Martins Dos Santos, V.A.P. +1 more
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In his editorial overview for the 2008 Special Issue on this topic, the late Jaroslav Stark pointedly noted that systems biology is no longer a niche pursuit, but a recognized discipline in its own right “noisily” coming of age [1]. Whilst general underlying principles and basic techniques are now reasonably well established, we see a progressive shift
Martins Dos Santos, V.A.P. +1 more
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