Results 161 to 170 of about 1,058,962 (296)

Formalization of System Engineering Processes (Proposal of a method to adapt generic processes to different application contexts)

, 2007
Samuel Rochet, BARON, Claude
openalex   +1 more source

A systems biology pipeline identifies regulatory networks for stem cell engineering

, 2019
Melissa A. Kinney, Linda T. Vo, Jenna M. Frame, Jessica Barragan, Ashlee J. Conway, Shuai Li, Kwok‐Kin Wong, James J. Collins, Patrick Cahan, Trista E. North, Douglas A. Lauffenburger, George Q. Daley   +11 more
openalex   +2 more sources

Capabilities Engineering: Constructing Change-Tolerant Systems [PDF]

, 2006
Ramya Ravichandar, James D. Arthur, Shawn Bohner   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Stimuli-Responsive, Cell-Mediated Drug Delivery Systems: Engineering Smart Cellular Vehicles for Precision Therapeutics. [PDF]

Pharmaceutics
Mashele SS.
europepmc   +1 more source

Characterizing barriers to antibiotic stewardship for skin and soft-tissue infections in the emergency department using a systems engineering framework. [PDF]

Antimicrob Steward Healthc Epidemiol, 2022
Pulia MS, Schwei RJ, Hesse SP, Werner NE.   +3 more
europepmc   +1 more source

Organizing IoT Systems-of-Systems from standardized engineering data

, 2016
Oscar Carlsson, Csaba Hegedűs, Jerker Delsing, Pál Varga   +3 more
openalex   +2 more sources

Supporting Computational Data for publication: "Engineering Improved Ethylene Production: Leveraging Systems Biology and Adaptive Laboratory Evolution"

, 2021
Christof Jaeger
openalex   +1 more source

Computer Engineering Solutions in Smart Systems [PDF]

, 2020

openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source