Results 221 to 230 of about 4,736,102 (330)
Model-Based Systems Engineering Applied to Trade-Off Analysis of Wireless Power Transfer Technologies for Implanted Biomedical Microdevices. [PDF]
Martínez Rojas JA +4 more
europepmc +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Systems engineering of Escherichia coli for high-level glutarate production from glucose. [PDF]
Zhang Z +8 more
europepmc +1 more source
How systems engineering can improve care in the ICU. [PDF]
Lecamwasam H +4 more
europepmc +1 more source
Theory of technical systems: a total concept theory for engineering design [PDF]
Vladimir Hubka, W. Ernst Eder
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

