Results 31 to 40 of about 3,460 (248)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Localized direct segregated boundary-domain integral equations for variable-coefficient transmission problems with interface crack [PDF]

, 2011
The full text of the published article can be accessed at the link belowSome transmission problems for scalar second order elliptic partial differential equations are considered in a bounded composite domain consisting of adjacent anisotropic subdomains ...
Mikhailov, SE, Natroshvili, D, Chkadua, O   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Wavelet formulation of the polarizable continuum model. II. Use of piecewise bilinear boundary elements [PDF]

, 2015
The simplicity of dielectric continuum models has made them a standard tool in almost any Quantum Chemistry (QC) package. Despite being intuitive from a physical point of view, the actual electrostatic problem at the cavity boundary is challenging: the ...
Simen Sommerfelt Reine, Mozgawa, Krzysztof, Helmut Harbrecht, Krzysztof Mozgawa, Reine, Simen Sommerfelt, Monica Bugeanu, Bugeanu, Monica, Reine, Simen, Di Remigio, Roberto, Frediani, Luca, Roberto Di Remigio, Luca Frediani, Harbrecht, Helmut   +12 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Efficient numerical methods for Volterra integral equations of Hammerstein type [PDF]

, 2006
Volterra integral equations (VIEs) are the mathematical model of many evolutionary problems with memory arising from biology, chemistry, physics, engineering.
Del Prete, Ida
core  

Generalized fractional controller for singular systems of differential equations [PDF]

, 2023
In this article we consider a class of singular linear systems of first order, and introduce a generalized fractional order feedback controller of Caputo type.
Dassios, Ioannis K., Milano, Federico, Tzounas, Georgios   +2 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On the asymptotic behaviour of deterministic and stochastic volterra integro-differential equations [PDF]

, 2007
This thesis examines a question of stability in stochastic and deterministic systems with memory, and involves studying the asymptotic properties of Volterra integro-differential equations.
Devin, Siobhan
core