Results 251 to 260 of about 581,117 (305)

Systems Pharmacology and Pharmacodynamics

CPT: Pharmacometrics & Systems Pharmacology, 2017
openaire   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

An integrated quantitative systems pharmacology virtual population approach for calibration with oncology efficacy endpoints. [PDF]

CPT Pharmacometrics Syst Pharmacol
Braniff N, Joshi T, Cassidy T, Trogdon M, Kumar R, Poels K, Allen R, Musante CJ, Shtylla B.   +8 more
europepmc   +1 more source

Systems pharmacology-based optimization of Ma Xing Shi Gan components for the enhanced treatment of chick health issues caused by infectious bronchitis virus. [PDF]

Front Cell Infect Microbiol
Liu H, He Y, Wang C, Wei X, Chen J, Wang K.   +5 more
europepmc   +1 more source

Global sensitivity analysis of Open Systems Pharmacology Suite physiologically based pharmacokinetic models. [PDF]

CPT Pharmacometrics Syst Pharmacol
Najjar A, Hamadeh A, Krause S, Schepky A, Edginton A.   +4 more
europepmc   +1 more source

Augmented intelligence in precision medicine: Transforming clinical decision-making with AI/ML and/or quantitative systems pharmacology models. [PDF]

Clin Transl Sci
Venkatapurapu SP, Gibbs M, Kimko H.
europepmc   +1 more source

Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study. [PDF]

FEBS Lett
Lawrence S, Lin J, Khurshid A, Utami W, Singhania R, Ashraf S, Thorn GJ, Mangangcha IR, Spriggs K, Kim DH, Barrett D, de Moor CH.   +11 more
europepmc   +1 more source

Landscape of regulatory quantitative systems pharmacology submissions to the U.S. Food and Drug Administration: An update report. [PDF]

CPT Pharmacometrics Syst Pharmacol
Bai JPF, Liu G, Zhao M, Wang J, Xiong Y, Truong T, Earp JC, Yang Y, Liu J, Zhu H, Burckart GJ.   +10 more
europepmc   +1 more source