Results 61 to 70 of about 516,786 (317)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Changing Homeland Security Shape Patterns, Not Programs [PDF]

open access: yes, 2006
This article appeared in Homeland Security Affairs (October 2006), v.2 no.3What is a homeland security future worth creating? After enough discussion, the homeland security community could probably agree on the broad outlines of a desirable future ...
Bellavita, Christopher
core  

Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada [PDF]

open access: yes, 2007
Corrective Action Unit (CAU) 224 is located in Areas 02, 03, 05, 06, 11, and 23 of the Nevada Test Site, which is situated approximately 65 miles northwest of Las Vegas, Nevada. CAU 224 is listed in the Federal Facility Agreement and Consent Order (FFACO)
National Security Technologies, LLC
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Patterns of information security postures for socio-technical systems and systems-of-systems [PDF]

open access: yes, 2012
This paper describes a proposal to develop patterns of security postures for computer based socio-technical systems and systems-of-systems.
Storer, T., Glisson, W., Renaud, K.
core  

TIA: algorithms for development of identity-linked SNP islands for analysis by massively parallel DNA sequencing

open access: yesBMC Bioinformatics, 2018
Background Single nucleotide polymorphisms (SNPs) located within the human genome have been shown to have utility as markers of identity in the differentiation of DNA from individual contributors.
M. Heath Farris   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Natural Security for a Variable and Risk-Filled World [PDF]

open access: yes, 2010
This article appeared in Homeland Security Affairs (September 2010), v.6 no.3The twenty-first-century faces a range of severe threats to security including conflicts with non-state actors, emerging diseases, natural disasters, cyber-attacks, and climate ...
Sagarin, Raphael
core  

Quality of Security Service [PDF]

open access: yes, 2000
We examine the concept of security as a dimension of Quality of Service in distributed systems. Implicit to the concept of Quality of Service is the notion of choice or variation.
Levin, Timothy E.   +3 more
core   +1 more source

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