Results 151 to 160 of about 187,101 (264)

Systems Thinking About SARS-CoV-2

Frontiers in Public Health, 2020
Rainer Johannes Klement
doaj   +1 more source

Using systems thinking to guide the dissemination of the European code against cancer, 5th edition. [PDF]

Mol Oncol
D'Souza E, Ritchie D, Zeeb H, Schüz J, Espina C.   +4 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

The impact of nurses' perceptions of systems thinking on patient safety competencies: a cross-sectional study. [PDF]

BMC Health Serv Res
Kakemam E, Mardani A, Parsarad E, Taheri R, Moosavi S, Kalhor R, Roh YS.   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Scientists' Warning to Humanity: The Need to Begin Teaching Critical and Systems Thinking Early in Life. [PDF]

Microb Biotechnol
Timmis K, Baquero F, Lal R, Amorim LRP, Nikel PI, Kaur J, Sood U, Lata P, Singh S, Robinson JM, Chavarria M, Verstraete W, Bernal P, Banciu H, Steward K, Frey J, Danchin A, Karnkowska A, Kotsyurbenko O, Pereira CS, Boyd ES, Hallsworth JE, Nunes O, Udaondo Z, Huang W, Wang Y, Karahan ZC, Junier P, Ron E, Ramos JL.   +29 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Building a resilient oncology workforce in the Asia-Pacific: From outcomes to systems thinking in workforce well-being. [PDF]

Asia Pac J Oncol Nurs
Adapa K, Venketa AY, Reji M, Mazur L, Vizer L, Bissram J, Kertcher E, Charguia N.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Applying a systems thinking approach to evaluating the effectiveness of Africa's foodborne disease surveillance systems. [PDF]

Commun Med (Lond)
Thystrup C, Ogunbiyi T, Hald T.
europepmc   +1 more source