Results 51 to 60 of about 1,991,043 (280)

Care Management and Cost Control in Pediatric Accountable Care Organizations: A Comparative Case Study [PDF]

open access: yesHealth Economics and Management Review
As accountable care organizations have proliferated across the healthcare landscape, research into the factors contributing to accountable care organization development for adults has identified useful approaches to managing care under this care model ...
Ann Scheck McAlearney   +3 more
doaj   +1 more source

Managing systemic risk using systems thinking in practice [PDF]

open access: yes, 2013
Managing uncertainties associated with, say, water security, toxic wastes, or biotechnology, invites growing relevance from the field of complexity sciences that everything is connected.
Reynolds, Martin
core  

Collaborative Systems Thinking: Towards an Understanding of Team-level Systems Thinking [PDF]

open access: yes, 2008
As the engineering workforce ages, skills with long development periods are lost with retiring individuals faster than are younger engineers developing the skills. Systems thinking is one such skill.
Kissane, M.P.   +3 more
core   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Assessment of Patient Experience During Active Surveillance for Prostate Cancer

open access: yesJournal of Patient Experience
Active surveillance is a preferred strategy for patients with low-risk prostate cancer to delay and/or avoid side effects of treatment. While its impact on health-related quality of life (HRQOL) has been studied, factors influencing follow-up adherence ...
Devon M. Langston   +8 more
doaj   +1 more source

Systems Thinking Principles for Making Change

open access: yesSystems
Traditionally, systems thinking support has relied on an ever-increasing plethora of systems tools, methods, and approaches. Arguably though, such support requires something different from, and more accessible than, detailed instruction on somewhat ...
Martin Reynolds
doaj   +1 more source

Redesigning Systems Thinking

open access: yesFORMakademisk, 2017
The resent movement of Systemic Design seeks for new synergies between Design and Systems. While the usefulness of systems approaches in design has been fairly obvious, this paper argues that many core concepts in design are beneficial in systems ...
Birger Sevaldson
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Framing purposeful evaluation through critical systems thinking [PDF]

open access: yes, 2007
Two traditions of practice – evaluation and systems – share three significant concerns regarding development intervention: (i) making sense of complex interrelationships and the continual change brought about by such relationships; (ii) engaging with ...
Reynolds, Martin
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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