Results 171 to 180 of about 64,835 (288)

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Nature de la systole des ventricules du coeur considérée comme acte musculaire

open access: yes
NATURE DE LA SYSTOLE DES VENTRICULES DU COEUR CONSIDÉRÉE COMME ACTE MUSCULAIRE Nature de la systole des ventricules du coeur considérée comme acte musculaire (63) (-
Marey, Étienne Jules
core   +1 more source

The Extracellular Matrix Proteins Pericardin and Lonely Heart Modulate the Directionality of Heart Contractions in Infected Mosquitoes

open access: yesArchives of Insect Biochemistry and Physiology, Volume 123, Issue 1, September 2026.
Pericardin and Lonely heart, which are components of the cardiac extracellular matrix, influence the direction in which the heart of mosquitoes propels hemolymph (blood). ABSTRACT The cardiac extracellular matrix provides structural support to the primary circulatory organ of an insect: a dorsal vessel that is divided into an aorta in the thorax and a ...
Shabbir Ahmed   +2 more
wiley   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

open access: yesArthritis &Rheumatology, Volume 78, Issue 9, Page 1892-1906, September 2026.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu   +12 more
wiley   +1 more source

Rational and design of the digital diagnosis of cardiac sounds in paediatric patients (DI_SOUND) study. [PDF]

open access: yesEur Heart J Digit Health
Egidy Assenza G   +18 more
europepmc   +1 more source

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