Results 41 to 50 of about 54,609 (316)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Hubungan Kesepian dengan Gangguan Pola Tidur pada Lansia Hipertensi dan Tidak Hipertensi di UPT PSTW Banyuwangi

NERS Jurnal Keperawatan, 2022
Loneliness affected sleep disorders among the elderly. A poor sleep pattern will be increasing blood pressure among elderly. The aimed his study was to analyzed the correlation between loneliness and sleep disorder among the elderly with hypertension.
Insyaf Prawita Sari, Latifa Aini Susumaningrum, Hanny Rasni, Tantut Susanto, Diana Kholida   +4 more
doaj   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Myocardial Bridging: A cause for concern?

Liječnički vjesnik, 2023
Myocardial bridging(MB) is a condition where a segment of a coronary artery, which normally runs on the surface of the heart muscle, instead dives into the heart muscle and then re-emerges to continue its normal path.
Marin Boban, Antun Zvonimir Kovač, Mladen Jukić, Petar Medaković   +3 more
doaj   +1 more source

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

Animal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak, Lenka Tomasova, Marian Grman, Karol Ondrias   +3 more
wiley   +1 more source

Terapi Bekam dan Akupunktur Terhadap Penurunan Tekanan Darah pada Penderita Hipertensi Primer (Esensial) di Klinik Herbal El Zahra Kota Tarakan

Jurnal Ners dan Kebidanan Indonesia, 2014
Hypertension is health problems are often happens in society, both of urban and rural community. Prevalence in Indonesia reached was 75.8% quite high, the long term medical treatment make it more difficult to handled properly.
Yumira Ria Santi, Yhona Paratmanitya, Pratiwi Pratiwi   +2 more
doaj   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

A proof of concept treatment planning study of gated proton radiotherapy for cardiac soft tissue sarcoma

Physics and Imaging in Radiation Oncology, 2021
Background and Purpose: Few studies on radiotherapy of cardiac targets exist, and none using a gating method according to cardiac movement. This study aimed to evaluate the dose-volume advantage of using cardiac-respiratory double gating (CRDG) in terms ...
Hyeri Lee, Jennifer Pursley, Hsiao-Ming Lu, Judith Adams, Thomas DeLaney, Yen-Lin Chen, Kyung-Wook Jee   +6 more
doaj   +1 more source