Results 71 to 80 of about 93,314 (285)

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Diastolic-systolic velocity ratio to detect coronary stenoses under physiological resting conditions: a mechanistic study

Open Heart, 2019
Objective Diastolic-systolic velocity ratio (DSVR) is a resting index to assess stenoses in the left anterior descending artery (LAD). DSVR can be measured by echocardiographic or intracoronary Doppler flow velocity.
Jan J Piek, Javier Escaned, Guus A de Waard, Christopher J Broyd, Christopher M Cook, Nina W van der Hoeven, Ricardo Petraco, Sukhjinder S Nijjer, Tim P van de Hoef, Mauro Echavarria-Pinto, Martijn Meuwissen, Sayan Sen, Paul Knaapen, Niels van Royen, Justin E Davies   +14 more
doaj   +1 more source

Stable systolic category of the product of spheres

, 2010
The stable systolic category of a closed manifold M indicates the complexity in the sense of volume. This is a homotopy invariant, even though it is defined by some relations between homological volumes on M.
Berger, Federer, Gromov, Hoil Ryu
core   +1 more source

Systolic ventricular filling [PDF]

European Journal of Cardio-Thoracic Surgery, 2004
The evidence of the ventricular myocardial band (VMB) has revealed unavoidable coherence and mutual coupling of form and function in the ventricular myocardium, making it possible to understand the principles governing electrical, mechanical and energetical events within the human heart.
Francisco, Torrent-Guasp, Mladen J, Kocica, Antonio, Corno, Masashi, Komeda, James, Cox, A, Flotats, Manel, Ballester-Rodes, Francesc, Carreras-Costa   +7 more
openaire   +2 more sources

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Differences in Serum Lipid Profile Value in Pregnancy and Postpartum on Severe Preeclampsia

Indonesian Journal of Obstetrics and Gynecology, 2019
Objective:Uncovering the connection of serum lipid profile (total cholesterol, triglyceride, HDL, LDL, VLDL) with preeclampsia in pregnancy and postpartum, and its outcome.
I Putu F I White, John J E Wantania, Maya E Mewengkang   +2 more
doaj   +1 more source

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

The injectivity radius of hyperbolic surfaces and some Morse functions over moduli spaces

, 2015
This article is devoted to the variational study of two functions defined over some Teichmueller spaces of hyperbolic surfaces. One is the systole of geodesic loops based at some fixed point, and the other one is the systole of arcs.\par For each of them
Gendulphe, Matthieu
core   +1 more source