Results 181 to 190 of about 5,906,243 (300)

Impact of coronary artery disease on systolic function in severe aortic stenosis-a multimodality imaging study. [PDF]

Eur Heart J Imaging Methods Pract
Hälvä R, Vaara S, Syväranta S, Holmström M, Federico J, Kaasalainen T, Peltonen J, Suihko S, Lommi J, Niemi H, Uusitalo V.   +10 more
europepmc   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Association Between Systemic Inflammation Response Index, Worsening of Left Ventricular Systolic Function and Prognosis in Patients with Coronary Artery Disease. [PDF]

J Inflamm Res
Ruan H, Lu X, Lu H, Huang H, Huang Z, Tang S, Yuan Z, Jiang R, Xin J, Tang T, Liu J, Liu Y, Tan N.   +12 more
europepmc   +1 more source

A Pilot Randomized Study of NAT2 and YEATS4 Pharmacogenetic Return of Results in Adults with Hypertension and African Ancestry: The GUARDD‐US PGx Study

Clinical Pharmacology &Therapeutics, EarlyView.
Almost half of individuals with hypertension fail to achieve recommended blood pressure (BP) goals. Pharmacogenetic gene‐drug interactions may alter the efficacy of antihypertensive agents. We conducted a multicenter randomized controlled sub‐study of participants (N = 1874) with hypertension and self‐reported African ancestry to determine whether ...
Philip E. Empey, Nita A. Limdi, Dinushika Mohottige, Kady‐Ann Steen‐Burrell, Hrishikesh Chakraborty, Khoa A. Nguyen, Alexander S. Parker, Emily J. Cicali, Girish N. Nadkarni, Michelle A. Ramos, Sabrina Clermont, Erica N. Elwood, Mimsie Robinson, Nandini Shroff, Marc B. Rosenman, Ronald Huang, Larisa H. Cavallari, Julie A. Johnson, Paul R. Dexter, Todd C. Skaar, Kerri L. Cavanaugh, Christina M. Wyatt, Carol R. Horowitz, Rhonda M. Cooper‐DeHoff, Michael T. Eadon, on behalf of the IGNITE Pragmatic Trials Network   +25 more
wiley   +1 more source

Investigation into the efficacy of fully automated three-dimensional echocardiographic quantification software (3D Auto RV) for assessing right ventricular systolic function in patients suffering from chronic mountain sickness. [PDF]

Front Cardiovasc Med
Zhao J, Zhao X, Chen X.
europepmc   +1 more source

Red Blood Cell Surface Proteins and Cryopreservation for Tracking Altered Erythropoiesis

Drug Testing and Analysis, EarlyView.
Recombinant human erythropoietin altered red blood cell surface protein expression, but responses were inconsistent and accompanied by substantial baseline variability. Although cryopreservation reduced analytical variability, it did not improve biomarker performance, indicating limited utility for detecting altered erythropoiesis. ABSTRACT The present
Martin Thomassen, Thomas Bonne, Jonathan Graae, Sophie Møller, Ylva Hellsten, Henrik Sørensen, Nikolai B. Nordsborg, Jacob Bejder   +7 more
wiley   +1 more source

Enhanced cardiac sympathetic innervation predicts systolic function improvement and outcome in dilated cardiomyopathy. [PDF]

Cardiol J
Dziewięcka E, Holcman K, Kostkiewicz M, Szot W, Wiśniowska-Śmiałek S, Winiarczyk M, Stępień-Wroniecka A, Graczyk K, Przytuła N, Rubiś P.   +9 more
europepmc   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

Deep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu, Dawei Cui, Yingjie Liu, Yuntao Liang, Yue Zhang   +4 more
wiley   +1 more source

Spermidine preserves cardiac systolic function in estrogen-deprived rats with accelerated aging via metabolic and mitochondrial reprogramming. [PDF]

Sci Rep
Kaorop W, Maneechote C, Pratchayasakul W, Kumfu S, Arunsak B, Kongkaew A, Chattipakorn SC, Chattipakorn N.   +7 more
europepmc   +1 more source

Cognitive Behavioral Therapy for Binge‐Eating Disorder in Individuals With Type 2 Diabetes: A Pilot Randomized Controlled Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To evaluate the feasibility of a randomized pilot trial of group‐based cognitive behavioral therapy (CBT) for binge eating disorder (BED) in individuals with type 2 diabetes, and to estimate exploratory clinical outcomes to inform the design of a future efficacy trial. Method Thirty‐four participants with type 2 diabetes and BED were
Pernille Fiil Nybo, Michael Einar Røder, Mia Beck Lichtenstein, René Klinkby Støving, Jakob Linnet   +4 more
wiley   +1 more source