Results 41 to 50 of about 5,906,243 (300)

State-of-the-art methodologies used in preclinical studies to assess left ventricular diastolic and systolic function in mice, pitfalls and troubleshooting

open access: yesFrontiers in Cardiovascular Medicine, 2023
Cardiovascular diseases (CVD) are still the leading cause of death worldwide. The improved survival of patients with comorbidities such as type 2 diabetes, hypertension, obesity together with the extension of life expectancy contributes to raise the ...
Gianluigi Pironti, Gianluigi Pironti
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

The comparison of 2D and 3D speckle-tracking echocardiography values in young athletes

open access: yesСпортивная медицина: наука и практика, 2020
Objective: to analyze the parameters of 2D and 3D transthoracic echocardiography (TEE) with speckle-tracking technology in young athletes. Materials and methods: 79 athletes (52 male, 27 female, median age 20,5±3,7 years) undergone prospective analysis ...
O. P. Mamaeva   +5 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu   +7 more
wiley   +1 more source

[Dyspnea and normal systolic function].

open access: yesHerz, 2005
30-50% of patients presenting with symptoms of congestive heart failure exhibit a near normal left ventricular systolic function at rest, and an impaired diastolic function of the heart may be causative. Despite a better prognosis than in systolic heart failure, frequency of hospitalizations due to diastolic heart failure is comparable with systolic ...
Hasenfuß, Gerd   +2 more
openaire   +2 more sources

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Parkinson’s Disease and the Cardiac Cycle: A Rapid Literature Review and Case Series

open access: yesLife, 2023
Background and Objectives: Cardiac function in patients with Parkinson’s Disease (PD) is not well understood. We conducted a review of the literature to summarize all available data on the cardiac cycle in patients with PD and followed up the review with
Holly Bardutz   +3 more
doaj   +1 more source

Mapping Packet Processing Applications on a Systolic Array Network Processor [PDF]

open access: yes, 2008
Systolic array network processors represent an effective alternative to ASICs for the design of multi-gigabit packet switching and forwarding devices because of their flexibility, high aggregate throughput and deterministic worst-case performances ...
Rolando, Pierluigi,   +16 more
core   +1 more source

Video 1. An echocardiogram showed reduced right ventricular (RV) systolic function and McConneal sign.

open access: yes, 2022
Video. An echocardiogram showed reduced right ventricular (RV) systolic function and McConneal sign.
Dwi Fachrul Octafian Hidayat (13119909)   +4 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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