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A phase 2 randomized, placebo-controlled study on the efficacy and safety of AR1001, a phosphodiesterase-5 inhibitor, in patients with mild-to-moderate Alzheimer's disease. [PDF]

open access: yesJ Prev Alzheimers Dis
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Organizing a tête-à-tête between cell adhesion molecules and extracellular proteases: a risky business that could lead to the survival of tumor cells

Frontiers in Bioscience, 2005
Several membrane-bound molecules expressed at the surface of tumor cells have been shown to be released in a soluble form, thereby affecting cell-cell interactions by reduction of ligand densities. Moreover, since the binding domain of the soluble molecules often remains functional, proteolytic cleavage can also reduce the recognition of tumor cells by
openaire   +3 more sources

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