Results 121 to 130 of about 313,523 (292)

Molecular and Clinical Characterization of the Hb Tübingen [β106(G8) Leu→ Gln, HBB: c.320 T>A] Associated With Congenital Methemoglobinemia in a Chinese Family

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Congenital methemoglobinemia caused by hemoglobin variants is a rare hematological disorder often misdiagnosed due to overlapping features with enzymatic defects. Hb Tübingen, a β‐globin chain variant (βCD106), is characterized by increased autoxidation, heat instability, and cyanosis.
Hualei Luo   +7 more
wiley   +1 more source

Fritz Scheffer Under National Socialism: Assessing His Political Involvement

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Aims This article examines the role of soil scientist Fritz Scheffer (1899–1979) under National Socialism and offers a critical assessment of his scientific, institutional, and political positioning between 1933 and 1945. It asks how Scheffer shaped his career within the tension between disciplinary specialization, political expectations, and ...
Jan Arend
wiley   +1 more source

Considerações sobre o Bem em Platão

open access: yesKalagatos, 2017
Platão; Bem; Escola de Tübingen-Milão; Doutrinas não-escritas;
Maria Celeste de Sousa
doaj  

Mini‐Review: Angular Scattering and Directional Effects in Tip‐Enhanced Raman Spectroscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
Mini‐review: Angular scattering and directional effects in tip‐enhanced Raman spectroscopy. Felix Schneider, David Baschnagel, Tim Parker, Yang Zhao, Alfred J. Meixner*, Dai Zhang*. This mini‐review examines angular scattering and directional effects in tip‐enhanced Raman spectroscopy (TERS), emphasizing their importance for quantitative interpretation
Felix Schneider   +5 more
wiley   +1 more source

Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53

open access: yesDrug Design, Development and Therapy
Theresa Klett,1,* Martin Schwer,1,* Larissa N Ernst,1,* Marc U Engelhardt,1 Simon J Jaag,2 Benedikt Masberg,2 Cornelius Knappe,2 Michael Lämmerhofer,2 Matthias Gehringer,3,4 Frank M Boeckler1,5 1Laboratory for Molecular Design ...
Klett T   +9 more
doaj  

Should Dermatologists Recommend Direct‐to‐Consumer App‐Based Remote Diagnostics? An Ethical Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Dermatology patients still face barriers in accessing timely specialist care. As direct‐to‐consumer (DTC) apps for remote dermatological diagnostics proliferate, guidance is lacking. While promising efficiency and efficacy, their clinical—and ethical—legitimacy is not yet well established.
Sonja Mathes   +9 more
wiley   +1 more source

Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?

open access: yesThe Laryngoscope, EarlyView.
Sudden sensorineural hearing loss is traditionally treated with steroids, either orally and/or via intratympanic injections, and hyperbaric oxygen treatment (HBOT) has resurged in popularity as an adjunctive therapy. The study has not found any additional treatment benefit with adjunctive concurrent HBOT; however, HBOT might be of value to patients ...
Jennifer L. Spiegel   +9 more
wiley   +1 more source

Implementing the Palatal Plate for Robin Sequence Beyond the Originating Center: How I Do It

open access: yesThe Laryngoscope, EarlyView.
The treatment of upper airway obstruction in newborns with Robin sequence (RS) is challenging. We report our experience implementing the minimally invasive Tübingen palatal plate in a pediatric tertiary care center, detailing a step‐by‐step protocol and clinical outcomes from our first patient series.
Agnès Giuseppi   +8 more
wiley   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

open access: yesMacromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani   +6 more
wiley   +1 more source

Effects of Pallidal Deep Brain Stimulation on Speech and Swallowing in Pediatric Patients with Dystonia

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Bilateral globus pallidus internus deep brain stimulation (GPi‐DBS) is a proven safe and effective treatment in certain forms of idiopathic or inherited dystonia (ID/IN). Its effects in acquired dystonia such as in dyskinetic cerebral palsy (DCP) however vary widely.
Katerina Bernardi   +16 more
wiley   +1 more source

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