Results 51 to 60 of about 114,181 (227)
Evaluation of protein and lipid oxidative stress in the patients with postmenopausal osteoporosis [PDF]
, 2014 Objective: Oxidative stress may change cellular function in multiple pathological conditions, including osteoporosis. We aimed to determine malondialdehyde (MDA) levels, advanced oxidation protein pruducts (AOPP), levels end products of protein oxidation,
Banu Çavdaroğlu +3 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Giant solitary trichoepithelioma: A Case report [PDF]
, 2013 Trichoepithelioma is a benign cutaneus tumour originatingfrom hair follicles. It is most commonly found on theface and scalp. Histopathologic examination was composedof band-like nests of basaloid cells showing peripheralpalization, abortive hair papilla
Ahmet Pergel, Hasan Güçer, Recep Bedir
core
Clinical and demographic characteristics of 165 patients with lichen planus [PDF]
, 2014 Objective: Lichen planus (LP), is a papulosquamous inflammatory disease, which involves the skin, mucous membranes, nails and scalp. The incidence varies according to geographical regions.
Asena Çiğdem Doğramacı +4 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
GEÇ ORTA ÇAĞ AVRUPA’SINDA TIP VE TABABET
Ortaçağ Araştırmaları Dergisi, 2018 İbn Sina ve İbn Nefis başta olmak üzere, XII. ve XIII.yüzyıllarda tıp eserlerinin büyük bir çoğunluğu Arapçadan Latinceye çevrilmişve Tıp alanındaki bilgiler, Batı’ya bu yolla aktarılmıştır.
Abdulhalik Bakır
doaj
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Maltepe Askeri (Asâkir-i Mansûre) Hastanesi Hakkında Bazı Bilgiler
Lokman Hekim DergisiAmaç: Bu çalışmada Maltepe Askeri Hastanesi’nin ilk yıllarında geçirdiği onarımlar ile hizmette kaldığı süreçte hastaneye yapılan denetimlerin incelenmesi amaçlanmıştır.Yöntem: 1 Mayıs-20 Temmuz 2024 arasında gerçekleştirilen bu çalışmada klasik tarih ...
İsmail Yaşayanlar, Yasemin Ayyıldız
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source