Results 81 to 90 of about 114,181 (227)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Klinik Tıp Kütüphaneciliği

open access: yesBilgi Dünyası, 2008
Esasen tıp ve sağlık bilimleri literatürünü hasta yatağı başına ulaştırmayı öngören Klinik Tıp Kütüphaneciliği (KTK) uygulamaları, tıp ve sağlığa ilişkin bilgi erişim sorunlarına getirilen en güvenilir çözümlerden biri olmuştur. Günümüzde hekim ve sağlık
Nazlı Alkan
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Septic Pulmonary Embolism in a Patient Who Applied Turkish Delight to a Soft Tissue Abscess: An Interesting Case Report

open access: yesDüzce Tıp Fakültesi Dergisi
This case report aimed to discuss a rare instance of septic pulmonary embolism (SPE) secondary to a gluteal abscess that was attempted to be treated using the traditional method of applying a Turkish delight dressing.
Halil İbrahim Çalişir   +4 more
doaj   +1 more source

Characteristics of sexual violence towards males: a comparison of gay and heterosexual victims [PDF]

open access: yes, 2008
Bu çalışmada, 126 eşcinsel, 120 heteroseksüel erkekten oluşan bir örneklem grubunda erkeklere yönelik cinsel şiddetin özellikleri anket yoluyla araştırılmıştır. Araştırmanın amacı erkek eşcinsellere yönelik cinsel şiddetin betimsel özelliklerini iki grup
Akdaş Mitrani, Tevhide Aslı   +1 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Eser veren Galatasaraylılar [PDF]

open access: yes, 1981
Taha Toros Arşivi, Dosya Adı: Galatasarayİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...

core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

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