Results 21 to 30 of about 5,571 (156)
Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma
Veterinary Dermatology, Volume 31, Issue 6, Page 466-e124, December 2020., 2020 Background The aim of this study was to compare serum interleukin (IL)‐31 concentrations in dogs with lymphoma and mast cell tumours (MCT) without pruritus to those of healthy dogs. Hypothesis/Objectives To determine if IL‐31 plays a role in tumour pathogenesis and if IL‐31 could be a biological marker for disease progression.
Nataliia Ignatenko +8 more
wiley +1 more source
Veterinary Dermatology, Volume 31, Issue 2, Page 154-e30, April 2020., 2020 Background Thymic stromal lymphopoietin (TSLP) plays a key role in the development of allergic inflammation. Little is known about possible triggers of equine TSLP expression. Hypothesis To investigate TSLP expression in equine insect bite hypersensitivity (IBH) skin lesions.
Iva Cvitas +4 more
wiley +1 more source
Research on T Lymphocyte Subsets and NK Cells Activity in Peripheral Blood of Hypopharyngeal Squamous Cell Carcinoma [PDF]
, 2017 目的:分析下咽鳞状细胞癌患者外周血T淋巴细胞亚群和NK细胞活性情况,旨在为相关研究工作提供参考资料。方法:择取2011年6月-2016年5月本院收治的95例下咽鳞状细胞癌病患为病例组,另取此期间内来本院接受健康检查的72例志愿者为正常组。使用流式细胞仪对病患开展相关检查,分析病例组与正常组的淋巴细胞亚群、NK活性情况以及不同临床分期的下咽癌病患外周血T淋巴细胞亚群以及NK细胞活性之间的关系。结果:与正常组相比,病例组的NK细胞、总B淋巴细胞、总T淋巴细胞、辅助/抑制T细胞、辅助T细胞偏低(P0.05 ...
刘存山 +7 more
core +1 more source
Advancements in the research of immunomodulatory effects of radiation therapy: from basic to clinical [PDF]
, 2023 Previously, radiotherapy was considered to directly kill tumor cells by deoxyribonucleic acid double-strand break. Recent studies have found that radiotherapy can also produce positive and effective anti-tumor effect by upregulating local and systemic ...
WANG Yu, BI Nan
core +1 more source
CD4~+T淋巴细胞Kv1.3通道在大鼠动脉粥样硬化中的作用 [PDF]
, 2010 目的:探讨大鼠动脉粥样硬化(AS)模型中CD4+T淋巴细胞电压门控钾通道(Kv)Kv1.3的表达、功能及其在AS中的作用。方法:采用高脂饮食法建立大鼠动脉粥样硬化模型,流式细胞术分析淋巴细胞的比例,采用免疫磁珠法分离CD4+T淋巴细胞,研究脾组织CD4+T淋巴细胞Kv1.3mRNA表达、细胞内钙离子浓度及细胞因子分泌的变化。结果:(1)AS组脾组织CD4+T淋巴细胞占总T淋巴细胞比例较对照组明显升高(74.93%±2.15%vs67.80%±2.54 ...
巩燕 +4 more
core
Cutaneous epitheliotropic T‐cell lymphoma in a sugar glider (Petaurus breviceps)
Veterinary Dermatology, Volume 36, Issue 2, Page 218-221, April 2025.A 3‐year‐old male sugar glider presented with pruritus and alopecia primarily affecting the back and neck regions. Dermatologic diagnostics ruled out common causes. Skin biopsies revealed cutaneous epitheliotropic T‐cell lymphoma, a rare condition in sugar gliders. Despite treatment, the glider's condition worsened, leading to death.
Piercarlo Amati +3 more
wiley +1 more source
Applying TALEN and CRISPR/Cas9 Technique to Knock out the PD1 Gene in Human Primary T Lymphocytes [PDF]
, 2016 过继性细胞免疫治疗(adoptivecellularimmunotherapy)是将患者自体免疫细胞在体外处理，然后筛选并大量扩增具有高度特异性的肿瘤杀伤性免疫效应细胞，再回输到患者体内杀灭肿瘤的一种治疗方法，过继性T细胞治疗是一种很有前景的癌症治疗方法。体内T细胞在进行免疫应答时，T细胞活化需要双重信号的协同作用，分别是抗原呈递信号和协同刺激信号。协同刺激分子通过为淋巴细胞提供正性或负性的调控信号参与机体的免疫调控。肿瘤细胞会利用体内免疫调节过程，表达或分泌的一些分子，对T细胞进行负向调控 ...
李剑
core
A multicentric intermediate‐size B‐cell lymphoma with epitheliotropism in a Freiberger mare
Veterinary Dermatology, Volume 35, Issue 5, Page 573-577, October 2024.This report describes a multicentric intermediate‐size B‐cell lymphoma with epitheliotropism in a Freiberger mare affecting multiple mucous membranes, skin and internal organs. The clonal neoplastic B‐cell population was accompanied by numerous reactive polyclonal small T cells. Differential diagnoses for these unusual findings are discussed.
Inês Berenguer Veiga +6 more
wiley +1 more source
Role of Kv1. 3 channel of CD4--+ T lymphocytes in the formation of atherosclerosis in rat spleen [PDF]
, 2010 目的:探讨大鼠动脉粥样硬化(AS)模型中Cd4+T淋巴细胞电压门控钾通道(kV)kV1.3的表达、功能及其在AS中的作用。方法:采用高脂饮食法建立大鼠动脉粥样硬化模型,流式细胞术分析淋巴细胞的比例,采用免疫磁珠法分离Cd4+T淋巴细胞,研究脾组织Cd4+T淋巴细胞kV1.3MrnA表达、细胞内钙离子浓度及细胞因子分泌的变化。结果:(1)AS组脾组织Cd4+T淋巴细胞占总T淋巴细胞比例较对照组明显升高(74.93%±2.15%VS67.80%±2.54 ...
巩燕 +4 more
core