[Peripheral Blood Laboratory Test Results Combined with TCF1+CD8+ T Lymphocytes Ratio to Predict the Response and Prognosis of Immunotherapy to Advanced Lung Cancer]. [PDF]
Zhongguo Fei Ai Za Zhi, 2023 Luo H, Dai S, Li Y, Tian P, Li Q, Cai X.
europepmc +1 more source
Arsenic trioxide inhibits the reactivity of allograft memory CD8+T cell-mediated transplant rejection [PDF]
, 2014 摘要 目的：记忆性T细胞(Tm)是诱导移植物耐受的重要障碍，抑制其产生是从根本上解决加速性排斥，延长移植物生存期的关键。本文通过对T淋巴细胞功能缺陷鼠(裸鼠)过继转移CD8+记忆性T细胞，建立预致敏的心脏移植模型，并进一步研究了中药单体三氧化二砷（Arsenictrioxide，As2O3）对记忆性CD8+T介导的移植排斥的影响并探讨了其可能的机制。 方法：首先进行C57BL/6(B6)到BALB/c的皮肤移植，皮肤移植后一个月提取皮肤移植鼠CD8+Tm细胞，通过过继转移CD8 ...
李纯
core
The inhibiting effects of Zotarolimus on allograft organ transplantation and mechanism research [PDF]
, 2017 目的：器官移植术后的免疫排斥反应严重制约着移植患者生活质量。目前临床上进行器官移植的患者大多需要服用免疫抑制剂维持治疗，长期维持用药不仅有较强的毒副作用，而且给患者生活带来了极大的不便。因此，新型免疫抑制剂研发和应用是解决器官移植术后免疫排斥反应的迫切需求。本实验中，我们首次将雷帕霉素衍生物佐他莫司应用于器官移植，研究佐他莫司的免疫抑制作用及其可能的作用机制。 方法：建立BALB/c到C57BL/6小鼠同种异体心脏移植模型，观察对照组和佐他莫司给药组小鼠心脏移植物生存期 ...
李成
core
[Clinical efficacy and safety of venetoclax combined with multidrug chemotherapy in the treatment of 15 patients with relapsed or refractory early T-cell precursor acute lymphoblastic leukemia]. [PDF]
Zhonghua Xue Ye Xue Za Zhi, 2023 Kong JY +11 more
europepmc +1 more source
[Early aggressive anti-HBV therapy is beneficial to reduce the occurrence risk of liver cancer and reconstitution of immune function of HBV-specific T-lymphocyte]. [PDF]
Zhonghua Gan Zang Bing Za Zhi, 2023 Shi YJ, Zhang DZ.
europepmc +1 more source
[Clinical efficacy and safety of CLAE regimen for refractory/relapsed T cell acute lymphoblastic leukemia/lymphoma: a prospective, multicenter, single-arm study]. [PDF]
Zhonghua Xue Ye Xue Za ZhiLi Y +9 more
europepmc +1 more source
[Dysregulated proportion of intrahepatic Treg cells and Th17 along with CD8+ T lymphocytes drives disease progression after kasai biliary atresia surgery]. [PDF]
Zhonghua Gan Zang Bing Za Zhi, 2021 Liu LW +7 more
europepmc +1 more source
[Clinical characteristics and prognosis of children with T-lineage acute lymphoblastic leukemia: a single-center study]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiChen XY, Wang JY, Jiang H, Zhang WN.
europepmc +1 more source
[Current situation and prospect of minimal residual disease in pediatric T cell acute lymphoblastic leukemia]. [PDF]
Zhonghua Xue Ye Xue Za ZhiNiu FF, Gao C.
europepmc +1 more source
[CD7 CAR-T cells treat T-ALL relapsed after allogeneic hematopoietic stem cell transplantation: a case report]. [PDF]
Zhonghua Xue Ye Xue Za Zhi, 2023 Huang HJ +7 more
europepmc +1 more source