Zhongshan Daxue xuebao. Yixue kexue ban, 1993 用26例风湿热患者外周血淋巴细胞和血清分别加到原代培养的人胚心肌细胞和心肌间质细胞中,观察其对上述两种细胞的毒性作用,结果发现:①风湿性心脏炎患者外周血T淋巴细胞和血清抗心肌抗体对心肌细胞和心肌间质细胞均有毒性作用。②单纯风湿性关节炎患者和风湿性心脏病风湿活动静止期患者外周血T淋巴细胞和血清对心肌细胞和心肌间质细胞无毒性作用。提示体液免疫和细胞免疫均参与风湿性心脏炎的发病机制。
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