Results 11 to 20 of about 333,809 (260)

Cutaneous T-cell Lymphoma [PDF]

open access: yesCancer Control, 1998
Background: Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed of malignant helper T lymphocytes. An accurate diagnosis of early CTCL is difficult because of the varied clinical and histologic expressions of the disease. Methods:
, Glass   +5 more
openaire   +2 more sources

Immune evasion of mantle cell lymphoma: expression of B7-H1 leads to inhibited T-cell response to and killing of tumor cells

open access: yesHaematologica, 2013
Clinical trials of immunotherapy in mantle cell lymphoma have not yet delivered desirable results, partly because of the inhibitory machinery of the tumor and its microenvironment.
Lijuan Wang   +14 more
doaj   +1 more source

Upregulated Neuro-oncological Ventral Antigen 1 (NOVA1) Expression Is Specific to Mature and Immature T- and NK-Cell Lymphomas [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2016
Background: Recent studies have revealed that the splicing factor neuro-oncological ventral antigen 1 (NOVA1) is enriched in fibroblasts and accumulated T cells of tertiary lymphoid structures.
Eun Kyung Kim   +5 more
doaj   +1 more source

MicroRNA-150 enhances radiosensitivity by inhibiting the AKT pathway in NK/T cell lymphoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Radioresistance is a major challenge during the treatment of NK/T cell lymphoma. This study aimed to investigate the potential role of MicroRNA-150 (miR-150) in increase the sensitivities of NK/T cell lymphoma to ionizing radiation. Results In
Shao Jie Wu   +4 more
doaj   +1 more source

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

open access: yesScientific Reports, 2021
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones   +7 more
doaj   +1 more source

Comparison of Diagnostic Cytomorphology of Natural Killer/T-Cell Lymphoma (Nasal Type) in Conventional Smears, Liquid-Based Preparations, and Histopathology

open access: yesCase Reports in Pathology, 2018
Natural killer (NK)/T-cell lymphoma is formally referred to as extranodal NK/T-cell lymphoma, nasal type (ENKTCL), in the 2008 and 2016 World Health Organization (WHO) classifications.
Chih-Yi Liu, Hui-Chih Tsai
doaj   +1 more source

Nasal T cell lymphoma [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Middle aged adults are most frequently affected, with slight male predominance. The disease involves the nasal cavity and may spread to the pharynx, palate and larinx. Less frequently, orbital and cranial nerve involvement was described. Spreading to the skin, soft tissue and gastrointestinal tract may occur.
CUNEO, Antonio   +2 more
openaire   +3 more sources

A novel germline HAVCR2 (TIM-3) compound heterozygous mutation is related to hemophagocytic lymphohistiocytic syndrome in EBV-positive peripheral T-cell lymphoma (NOS) with down-regulated TIM-3 signaling

open access: yesFrontiers in Oncology, 2022
Recently, it have been reported that Hepatitis A Virus-Cellular Receptor 2(HAVCR2,encoding T-cell immunoglobulin and Mucin-Containing Protein 3[TIM3]) mutations are associated with severe hemophagocytic syndrome(HLH) in subcutaneous panniculitis-like T ...
Yang Zhang   +12 more
doaj   +1 more source

Genetic Landscape of Peripheral T-Cell Lymphoma

open access: yesLife, 2022
Peripheral T-Cell lymphoma (PTCL) comprises a heterogenous group of uncommon lymphomas derived from mature, post-thymic or “peripheral” T- and natural killer cells. The World Health Organization (WHO) emphasizes a multiparameter approach in the diagnosis
Vivian Hathuc, Friederike Kreisel
doaj   +1 more source

Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin’s lymphoma and T-cell non-Hodgkin’s lymphoma

open access: yesHaematologica, 2011
We recently reported deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia. Functional analyses confirmed that PTPN2 acts as classical tumor suppressor repressing the proliferation of T cells, in part through ...
Maria Kleppe   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy