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Critical Reviews in Oncology/Hematology, 2012
MCL is a well-characterized clinically aggressive lymphoma with a poor prognosis. Recent research findings have slightly improved the outcome of this neoplasm. The addition of rituximab to conventional chemotherapy has increased overall response rates, but it does not improve overall survival with respect to chemotherapy alone.
Cortelazzo S +3 more
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MCL is a well-characterized clinically aggressive lymphoma with a poor prognosis. Recent research findings have slightly improved the outcome of this neoplasm. The addition of rituximab to conventional chemotherapy has increased overall response rates, but it does not improve overall survival with respect to chemotherapy alone.
Cortelazzo S +3 more
openaire +4 more sources
Hematology/Oncology Clinics of North America, 2009
Peripheral T-cell lymphomas (PTCLs) are malignancies of immunologically mature T-cells that arise in peripheral lymphoid tissues such as lymph nodes, spleen, gastrointestinal tract, and skin. These lymphomas are uncommon as compared with the incidence of B-cell lymphomas, and they comprise only 5% to 10% of non-Hodgkin lymphomas in North America and ...
William R. Macon, William R. Macon
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Peripheral T-cell lymphomas (PTCLs) are malignancies of immunologically mature T-cells that arise in peripheral lymphoid tissues such as lymph nodes, spleen, gastrointestinal tract, and skin. These lymphomas are uncommon as compared with the incidence of B-cell lymphomas, and they comprise only 5% to 10% of non-Hodgkin lymphomas in North America and ...
William R. Macon, William R. Macon
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Angioimmunoblastic T-cell lymphoma
Critical Reviews in Oncology/Hematology, 2008Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive neoplasm clinically characterized by sudden onset of constitutional symptoms, lymphadenopathy, hepatosplenomegaly, frequent autoimmune phenomena, particularly hemolytic anemia and thrombocytopenia, and polyclonal hypergammaglobulinemia.
IANNITTO, EMILIO +4 more
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Angioimmunoblastic T-Cell Lymphoma
Hematology/Oncology Clinics of North America, 2017Angioimmunoblastic T-cell lymphoma is a follicular T-helper-derived neoplasm displaying a peculiar morphologic appearance and biological complexity. New mutations have been described that contribute to elucidating the underlying pathogenetic events. The disease behaves aggressively and typically affects elderly patients.
BROCCOLI, ALESSANDRO +1 more
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Expert Review of Anticancer Therapy, 2010
The T-cell Lymphoma Forum was held from 28-30 January, 2010, in Maui, HI, USA. The meeting provided a venue for clinicians and scientists to discuss the science and treatment of T-cell and natural killer (NK)-cell lymphomas. Different subtypes of T-cell and NK-cell lymphomas have different epidemiologic and clinicopathologic characteristics. T-cell and
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The T-cell Lymphoma Forum was held from 28-30 January, 2010, in Maui, HI, USA. The meeting provided a venue for clinicians and scientists to discuss the science and treatment of T-cell and natural killer (NK)-cell lymphomas. Different subtypes of T-cell and NK-cell lymphomas have different epidemiologic and clinicopathologic characteristics. T-cell and
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The Journal of Dermatology, 1980
AbstractCutaneous T cell lymphoma (CTCL) is a generic classification of clonally‐derived malignancies of phenotypic helper/inducer T cells with a propensity to infiltrate the skin, migrate into the epidermis, localize in T cell zones of lymphoid structures and spare the bone marrow.
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AbstractCutaneous T cell lymphoma (CTCL) is a generic classification of clonally‐derived malignancies of phenotypic helper/inducer T cells with a propensity to infiltrate the skin, migrate into the epidermis, localize in T cell zones of lymphoid structures and spare the bone marrow.
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T-cell therapies for T-cell lymphoma
Cytotherapy, 2019T-cell lymphomas represent a subpopulation of non-Hodgkin lymphomas with poor outcomes when treated with conventional chemotherapy. A variety of novel agents have been introduced as new treatment strategies either as first-line treatment or in conjunction with chemotherapy. Immunotherapy has been demonstrated to be a promising area for new therapeutics,
Keri Toner +2 more
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Current Hematologic Malignancy Reports, 2011
Most non-Hodgkin lymphomas (NHL) are of B-cell origin; only about 10% are T-cell or NK-cell lymphomas. The clinical features of T/NK-cell lymphomas differ from those of B-cell lymphomas: advanced stage and extranodal disease are more common and the prognosis is worse.
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Most non-Hodgkin lymphomas (NHL) are of B-cell origin; only about 10% are T-cell or NK-cell lymphomas. The clinical features of T/NK-cell lymphomas differ from those of B-cell lymphomas: advanced stage and extranodal disease are more common and the prognosis is worse.
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Blood, 2014
![Figure][1] A 30-year-old man with an unremarkable medical history presented with fever, anemia, and thrombocytopenia, along with hepatosplenomegaly, for >1 month. Laboratory findings for infectious etiology were nondiagnostic. He underwent surgical resection for splenomegaly.
April A. Ewton, Adeel Raza
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![Figure][1] A 30-year-old man with an unremarkable medical history presented with fever, anemia, and thrombocytopenia, along with hepatosplenomegaly, for >1 month. Laboratory findings for infectious etiology were nondiagnostic. He underwent surgical resection for splenomegaly.
April A. Ewton, Adeel Raza
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1992
Lymphoblastic lymphoma of T-cell type, originally known as the “convoluted cell type”, was recognized quite early. It was soon apparent that the tumour has its origin in the thymus or bone marrow and represents a lymphoma of immature T cells, i.e. a pre-thymic or thymic lymphoma.374 Lymphoblastic lymphoma of T-cell type must be distinguished clearly ...
Alfred C. Feller, Karl Lennert
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Lymphoblastic lymphoma of T-cell type, originally known as the “convoluted cell type”, was recognized quite early. It was soon apparent that the tumour has its origin in the thymus or bone marrow and represents a lymphoma of immature T cells, i.e. a pre-thymic or thymic lymphoma.374 Lymphoblastic lymphoma of T-cell type must be distinguished clearly ...
Alfred C. Feller, Karl Lennert
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