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The Formation and Selection of Cells Expressing PreB Cell Receptors and B Cell Receptors

1999
The repertoires of B cell receptor (Ig)-expressing B cells are generated during B cell development in a stepwise fashion (Tonegawa 1983). First, DH segments are rearranged to JH segments on the H chain locus at the transition from B220+CD19- proB cells to B220+CD19+ckit+ preB-I cells.
Jan Andersson   +4 more
openaire   +3 more sources

Cell Receptors for Picornaviruses

1990
The surfaces of animal cells bear specific receptor sites for different viruses. These sites are the first part of the host cell that viruses encounter as they begin the infectious cycle. Receptor binding has been studied as long as other events in the viral life cycle, yet with the exception of the influenza virus receptor, sialic acid, these studies ...
openaire   +3 more sources

T-Cell Receptor Purification

2003
The antigen receptor expressed on most T-lymphocytes (T-cell antigen receptor [TCR]) is a multisubunit complex consisting of at least six different polypeptides (α, β, γ, δ, ɛ, and ζ), several of which are modified by addition of N-linked oligosaccharide chains Oligosaccharide side chains on TCR glycoproteins undergo well-characterized processing ...
openaire   +3 more sources

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-vornhagen   +2 more
exaly  

The T-Cell Receptor Problem

1981
In 1972 M. Crone, C. Koch, and M. Simonsen published a paper entitled “The elusive T cell receptor” (Crone et al. 1972), which set the stage for almost a decade of research in this area. Since then progress has been achieved only in the manner of two steps forward and one step back.
openaire   +3 more sources

Structural basis of assembly of the human T cell receptor–CD3 complex

Nature, 2019
D. Dong   +9 more
semanticscholar   +1 more source

Regulatory mechanisms in T cell receptor signalling

Nature reviews. Immunology, 2018
G. Gaud, Renaud Lesourne, P. Love
semanticscholar   +1 more source

Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

Nature Cancer, 2019
Lan Wu   +35 more
semanticscholar   +1 more source

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