Generation of Photopolymerized Microparticles Based on PEGDA Hydrogel Using T-Junction Microfluidic Devices: Effect of the Flow Rates. [PDF]
Micromachines (Basel), 2023 Hinojosa-Ventura G +3 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Comprehensive development plan for Junction City, Oregon [PDF]
, 1973 42 pp. Boolmarks supplied by UO. Maps. Adopted November 13, 1973. Scanned by UO April, 2009.[T]he Comprehensive Development Plan for the City of Junction City, Oregon, was submitted to public hearing and was adopted by the City Council of Junction ...
Lane Council of Governments (Or.) +1 more
core +1 more source
Validation of Alternative Beam T-Junction Fem Models for Complex Tubular Structures. [PDF]
Materials (Basel), 2022 Badea F, Olazagoitia J, Perez J.
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Gas-liquid flow splitting in T-junction with inclined lateral arm
, 2018 This paper studies the gas-liquid flow splitting in T-junction with inclined lateral arm. The separation mechanism of the T-junction is related to the pressure distribution in the T-junction.
Yang Lele +11 more
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Turbulence induced shear controllable synthesis of nano FePO4 irregularly-shaped particles in a counter impinging jet flow T-junction reactor assisted by ultrasound irradiation. [PDF]
Ultrason Sonochem, 2023 Dong B +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Splitting of droplet with different sizes inside a symmetric T-junction microchannel using an electric field. [PDF]
Sci Rep, 2022 Fallah K, Fattahi E.
europepmc +1 more source