Results 291 to 300 of about 209,693 (354)

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho, Alexis E. McFeely, Daniel Skinner, Shaoyan Zhang, Justin Hedvat, Weslee Ping‐ay, Daniel M. Beswick, Justin H. Turner, Bradford A. Woodworth, Jie Xu   +9 more
wiley   +1 more source

Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications

American Journal of Hematology, EarlyView.
Robert T. Means Jr
wiley   +1 more source

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Differential Regulation of Murine T Lymphocyte Subsets

Annual Review of Immunology, 1993
Signaling pathways in T lymphocytes have been incompletely characterized. It is evident that differences exist among the T cell subsets. We have defined several distinct mechanisms that affect differentially the activities of murine T lymphocyte clones representing various CD4+ and CD8+ subsets: Interferon-gamma (IFN-gamma) inhibits proliferation of ...
F W, Fitch, M D, McKisic, D W, Lancki, T F, Gajewski   +3 more
openaire   +4 more sources

Activated T-Lymphocyte Subsets in Graves' Disease

New England Journal of Medicine, 1987
openaire   +4 more sources

T Lymphocyte Subsets in Uveitis

American Journal of Ophthalmology, 1983
We evaluated the peripheral T-cell subsets in 32 adult patients with intraocular inflammatory disease and 12 age-matched normal controls by means of the OKT series of monoclonal antibodies in conjunction with the laser cytofluorograph, which quantitatively determines the fluorescence intensity of lymphocytes.
R B, Nussenblatt, M, Salinas-Carmona, W, Leake, I, Scher   +3 more
openaire   +2 more sources

T‐Lymphocyte Subsets in Leprosy

International Journal of Dermatology, 1983
ABSTRACT:Immunologic abnormalities in T cells have been reported in patients with lepromatous leprosy. Ten patients with leprosy (eight lepromatous, one dimorphous, one tuber‐culoid) were studied in order to detect the proportions of total T lymphocytes and helper as well as suppressor subsets, using monoclonal antibodies in an indirect ...
R, Gonzalez-Amaro, B, Moncada, C E, Loredeo, M, de Lourdes Baranda   +3 more
openaire   +2 more sources

T-lymphocyte subsets in acute illness

Critical Care Medicine, 1995
To determine the range of T-lymphocyte subsets (CD4, CD8, and CD4/CD8 ratios) in acutely ill, hospitalized patients and to determine whether these concentrations correlate with illness severity, survival rate, or immunodepression.Cross-sectional study, comparing Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and the calculated ...
C, Feeney, S, Bryzman, L, Kong, H, Brazil, R, Deutsch, L C, Fritz   +5 more
openaire   +2 more sources

T‐lymphocyte subset distribution in human spleen

European Journal of Clinical Investigation, 2006
AbstractBackground  When analyzing human cellular immune responses, most focus is placed on the peripheral blood (PB) and, to a lesser extent, the lymph nodes. To date the spleen has not been analyzed with regard to its role in adaptive cellular immunity and more notably not with respect to T‐cell immune responses.Materials and methods  We analyzed the
Langeveld, M., Gamadia, L. E., ten Berge, I. J. M.   +2 more
openaire   +3 more sources

T-Lymphocyte Subsets in Adult Coeliac Disease

Clinical Science, 1983
1. As a defect of suppressor function has been hypothesized in the pathogenesis of coeliac disease, we measured, by monoclonal antibodies, the inducer/suppressor T-cell ratio in adult coeliac disease. 2. No statistical difference was observed between coeliac patients and healthy controls, irrespective of treatment and HLA status.
G R, Corazza, P, Tabacchi, M, Frisoni, M, Londei, D, Bastia, G, Gasbarrini   +5 more
openaire   +2 more sources

T lymphocyte subsets in Mediterranean spotted fever

Acta tropica, 1988
Several studies have previously suggested the possible role of a T lymphocyte suppressor population in infections by species of the genus Rickettsia. In 15 patients with Mediterranean spotted fever (MSF), we quantified, during the acute and convalescent phases of the disease, the peripheral blood lymphocyte populations using monoclonal antibodies that ...
J I, Herrero-Herrero, R, Ruiz-Beltrán, M, Cordero   +2 more
openaire   +2 more sources