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In Utero Per- and Polyfluoroalkyl Substances (PFAS) Exposure and Changes in Infant T Helper Cell Development among UPSIDE-ECHO Cohort Participants. [PDF]

open access: yesEnviron Health Perspect
Castro-Melendez D   +14 more
europepmc   +1 more source

Chemoattractant lymphokines specific for the helper/inducer T-lymphocyte subset

open access: yesCellular Immunology, 1985
The cellular content of T-lymphocyte-rich inflammatory sites is dependent in part on the in situ elaboration of chemoattractant factors. We have previously described three T-lymphocyte-specific chemoattractant lymphokines; a chemokinetic factor, lymphocyte chemoattractant factor (LCF, MW 56,000), and two distinct lymphocyte migration inhibitory factors
J S, Berman   +4 more
openaire   +3 more sources
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Unusual Lack of the Epitope Recognized by OKT4 on the Helper/Inducer T Lymphocytes

Pediatrics International, 1985
AbstractLack of the epitope recognized by OKT4 monoclonal antibody on the helper/inducer T lymphocytes in a 14‐year‐old boy with IgA nephritis is described.The lymphocytes reacted normally with OKT3 /Leu4 and OKT8/αLeu2a monoclonal antibodies but not with OKT4 monoclonal antibody.
Yoshitaka Fukunaga   +6 more
exaly   +2 more sources

Displacement of T Lymphocytes with the ‘Helper/Inducer’ Phenotype from Peripheral Blood to Lymphoid Organs in Untreated Patients with Hodgkin's Disease

Scandinavian Journal of Haematology, 1983
A panel of previously characterized monoclonal antibodies: B67.6, OKT3, OKT4, B53.4, Leu3a, OKT8, Leu2a, OKM1, M12 and B52.1 were used as a probe to assess mononuclear cells in peripheral blood (PB), lymph nodes (LN) and spleens of untreated patients with Hodgkin's disease (HD).
Enrico Maggi, Alberto Bosi
exaly   +4 more sources

DIETARY NUCLEOTIDES, A REQUIREMENT FOR HELPER/INDUCER T LYMPHOCYTES

Transplantation, 1985
Previous investigations have revealed that dietary nucleotide restriction delays the onset of primary murine cardiac allograft rejection and acute graft-versus-host disease followed H-2-incompatible bone marrow transplantation, suppresses sensitization to intradermally injected antigens and suppresses in vivo and in vitro lymphocyte proliferation to ...
C T, Van Buren   +3 more
openaire   +2 more sources

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

Science, 1984
Lymphadenopathy associated virus (LAV) has been isolated from patients with the acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome. Since the immune deficiency in AIDS seems to be primarily related to the defect of the helper-inducer T lymphocyte subset, the possibility that LAV is selectively tropic for this subset was investigated.
David Klatzmann   +10 more
openaire   +2 more sources

Abnormal distribution of the helper-inducer and suppressor-inducer T-lymphocyte subsets in the rheumatoid joint

Clinical Immunology and Immunopathology, 1987
T lymphocytes can be divided into two main phenotypic populations, CD4 and CD8. These can be further subdivided into 2H4, 4B4, or UCHL1 subsets by appropriate monoclonal antibodies. We have investigated these subsets in the synovial fluid of patients with rheumatoid arthritis and have found (i) a virtual absence of CD4+ 2H4+ and the marked reduction of
C, Pitzalis   +3 more
openaire   +2 more sources

The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion

European Journal of Immunology, 1988
AbstractThe mechanisms which lead to the accumulation of T lymphocytes into inflammatory lesions are not clearly understood. We have previously shown that synovial CD4 T lymphocytes are mostly CDw29UCHL1 (helper‐inducer cells) and very few carry the CD45R antigen which identifies the suppressor‐inducer subset.
C, Pitzalis   +3 more
openaire   +2 more sources

Heterogeneity of helper/inducer T lymphocytes. IV. Stimulation of resting and activated B cells by Th1 and Th2 clones.

The Journal of Immunology, 1990
Abstract To test the hypothesis that resting and previously activated B lymphocytes differ in their proliferative and differentiative responses to various Th cell-derived stimuli, we have examined the interactions of purified small (resting) and large (activated) murine B cells with rabbit Ig-specific Th1 and Th2 clones in the presence ...
A K, Abbas   +3 more
openaire   +2 more sources

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