Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Natural Ventilation Reduces Cooking-Related PM<sub>2.5</sub> Peaks Indoors. [PDF]
Su Y +5 more
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Linear reflected backward stochastic differential equations arising from vulnerable claims in markets with random horizon. [PDF]
Choulli T, Alsheyab S.
europepmc +1 more source
Fluctuations Around the Mean-Field Limit for Attractive Riesz Potentials in the Moderate Regime. [PDF]
Chen L, Holzinger A, Jüngel A.
europepmc +1 more source
The mechanism of mandatory exercise check-in on college students' intention to use fitness apps: a complete mediation model. [PDF]
Han Y, Li L.
europepmc +1 more source
Quantification of liver iron overload among pediatric patients with magnetic resonance imaging: current state of the art. [PDF]
Hryniewicz GA +4 more
europepmc +1 more source
Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia. [PDF]
Ibarra AJ +7 more
europepmc +1 more source
Comparison of cNORM and LMS methods for estimating reference percentile curves from biometric data. [PDF]
Laurenz R, Lenhard W.
europepmc +1 more source

