Results 161 to 170 of about 129,740 (272)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Bullying, Social Norms, and Reporting Behavior: A National Survey of Medical Training Programs. [PDF]

Fam Med
Terry DL, Graham J, Moore MA, Terry CP, Williamson MLC.   +4 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Changing the fate of rangelands through behavioral nudges for sustainable land use and management using an extended theory of planned behavior. [PDF]

Sci Rep
Valizadeh N, Bazrafkan K, Haji L, Karami S, Azadi H, Alinaghizadeh M.   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Using social norms to reduce plate waste in corporate dining. [PDF]

Sci Rep
Daker RJ, Del Mar Rojas M, Rakhimov R, Heffner K, Paine N, Cacciola K, Hanson C, Upritchard J.   +7 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

The emergence of cooperative behaviors, norms, and strategies across five diverse societies. [PDF]

Sci Adv
Amir D, Ahl RE, Jordan MR, Bolotin H, Bogese M, González GT, Callaghan T, Sugiyama LS, Otali E, Tusiime P, Bangayan S, Snodgrass JJ, McAuliffe K.   +12 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Impact of moral education on anomie behaviors in university students' physical education classes: serial mediation of attitudes toward sports norms and self-efficacy. [PDF]

BMC Psychol
Liu L, Song Y, Liu H, Chen S, Shang Y, Zhang Z.   +5 more
europepmc   +1 more source