Results 161 to 170 of about 11,150,608 (308)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Misses' coat-frock with sleeveless underblouse, 1919
, 1919 Pattern No. 4758: Underblouse with a shallow "modesty" trimmed with "narrow ruffles of organdie." Neckline and hem of blouse are trimmed with contrasting material. Narrow-collared waistcoat is finished along the back seams with buttons.
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Motricidad, 2010 <p class="resumenyabstract" align="justify">In the learning processes that promotes the generation of motor actions, teachers usually propose instructions based on kinetic models. The aim of this study is to observe what type of motor answers the subjects generate from kinesic models offered by the teachers.
M. Dinušová +3 more
openaire +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
, 1919 Pattern No. 4709: Square-necked nightgown with a yoke "trimmed with small tucks and an applied box plait at the center front." Sleeves are "gathered and finished at the lower edge with a narrow ruffle of lace." Gown is "trimmed with ruffles of narrow ...
Vogue Pattern Service
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Frock with blouse in Eton jacket effect, 1919
, 1919 Pattern No. 4771: Blouse with "narrow turn-over collar" and cuffed three-quarter length sleeves. Fullness of skirt is gathered to the lower edges of the blouse; in front, the blouse hangs over the skirt.
Vogue Pattern Service
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 1917 Pattern No. 3721: Dress with double collar, and sleeves that are "gathered to straight cuffs rolled back at the wrists and faced." Both the collars and cuff facings are of a contrasting material. Neckline is fastened with two button closures. Wide girdle
Vogue Pattern Service
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