Results 51 to 60 of about 526,591 (252)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Turkish Journal of Orthodontics, 2000 The aim of orthodontic treatment today has been expanded to include the ideal skeletal and functional relationships. This study was conducted on 9 girls and 11 boys, (total 20) between 13-15 years of age.
Gökhan Önçağ +4 more
doaj +1 more source
Journal of Oral Biology and Craniofacial Research, 2021 Introduction: Three-dimensional analysis of the moment, force and M/F ratio generated at the anterior and posterior region of the T-loop in five different groups of pre-activation curvatures using the finite element method.
Pooja Girsa +4 more
doaj +1 more source
T-scan system in the management of temporomandibular joint disorders – A review
Journal of Indian Academy of Oral Medicine and Radiology, 2019 Temporomandibular disorder (TMD) is a very common problem affecting up to 33% of individuals worldwide. TMD is a musculoskeletal disorder within the masticatory system presenting with typical signs and symptoms of pain, limited mouth opening, joint sounds, mandibular deviation, and chewing disability.
AncyV Ignatius +3 more
openaire +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
The EOS 3D imaging system reliably measures posterior tibial slope
Journal of Orthopaedic Surgery and Research, 2021 Background One of the values determined during the assessment of knee issues is the posterior tibial slope (PTS). A new option for measuring the PTS is the EOS 3D imaging system, which provides anteroposterior (AP) and lateral long leg radiographs (LLRs)
Andreas Hecker +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
International Journal of Food Properties, 2021 In this paper, an electrochemical sensor array utilizing metal materials was designed, and its applications in sugar content analysis from mixtures were conducted. The system adopts the conventional three-electrode system.
Xudong Fang +7 more
doaj +1 more source