Results 61 to 70 of about 29,215 (262)

IGA in CFD and FSI: Refinement Strategies, AI Integration, and Future Directions [PDF]

MATEC Web of Conferences
Isogeometric Analysis (IGA), introduced by Hughes et al. in 2005, seamlessly integrates CAD and FEA by directly utilizing NURBS, T-Splines, and Subdivision Surfaces in numerical simulations.
Guendaoui Sohaib, El Akkad Abdeslam, El Khalfi Ahmed   +2 more
doaj   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo   +3 more
wiley   +1 more source

A Novel Prognostic Model Incorporating Carcinoembryonic Antigen in 3-Week or Longer Postoperative Period for Stage III Colon Cancer: A Multicenter Retrospective Study

Frontiers in Oncology, 2020
BackgroundThe prognostic stratification of colon cancer using only the tumor-node-metastasis (TNM) stage has some limitations. We sought to increase the accuracy of stratifying patients with stage III colon cancer by constructing a prognostic model ...
Jin Fan, Jin Fan, Yanlong Liu, Xin Cai, Xin Cai, Jingwen Wang, Jingwen Wang, Rui Guo, Yuan Ji, Chao Li, Ye Xu, Ye Xu, Xinxiang Li, Xinxiang Li, Chundong Zhang, Chundong Zhang, Rui Zhang, Ji Zhu, Ji Zhu, Sanjun Cai, Sanjun Cai   +20 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration

Acta Clinica Croatica, 2017
The aim of the study was to assess diagnostic value and utility of selected morphological features in predicting lymph node (LN) malignancy using B-mode, Doppler ultrasonography and multivariate settings in a tertiary radiological referral center.
Tatjana Rotim, Branka Kristek, Tajana Turk, Domagoj Kretić, Marija Perić, Ivo Pušeljić, Tijana Pandurović, Mario Štefanić   +7 more
doaj   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Comparison of statistical modelling methods for population-level gestational weight gain trajectories in ethnically diverse women in southeast Melbourne, Australia

BMJ Open
Objectives Adverse lifestyle promotes escalating excess gestational weight gain (GWG) driving poor maternal and neonatal health outcomes. Recommended pregnancy lifestyle interventions rely on accurate assessment and prediction of GWG.
Rui Wang, Cheryce Harrison, Sanjeeva Ranasinha, Helena J Teede, Joanne Enticott   +4 more
doaj   +1 more source

T‐splines discretizations for large deformation contact problems [PDF]

PAMM, 2015
AbstractA T‐spline‐based isogeometric analysis is applied to frictional contact problems between deformable bodies in the context of large deformations. The continuum is discretized with cubic T‐splines and cubic NURBS (Non‐Uniform Rational B‐Splines) for comparison purposes.
DIMITRI, ROSSANA, ZAVARISE, Giorgio
openaire   +3 more sources

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source

Disorder‐Driven Fast Na+ Transport: From Crystalline to Amorphous Networks in the Mixed‐Anion NaTaOxCl6−2x Oxychlorides

Advanced Energy Materials, EarlyView.
Oxygen substitution in NaTaOxCl6‐2x drives structural evolution from isolated [TaCl6]– octahedra, through oxygen‐bridged [Ta2OCl10]2– dimers, toward extended trans‐[TaO2Cl4]3– chain‐like arrangements. At intermediate compositions, zero‐dimensional corner‐sharing motifs are proposed to create a flexible, disordered framework that peaks ionic ...
Justin Leifeld, Abigail C. Parsons, Alexandra Morscher, Xabier Martinez de Irujo‐Labalde, Marvin A. Kraft, Oskar G. Soulas, Bibek Samanta, Wiebke Zielasko, Neelam Yadav, Kyra Strotmann, Niina Jalarvo, Bruno V. M. Rodrigues, Adam Slabon, Philipp Adelhelm, Michael Ryan Hansen, David O. Scanlon, Wolfgang G. Zeier, Alexander G. Squires   +17 more
wiley   +1 more source