Results 41 to 50 of about 1,516,601 (262)

Accelerated cardiac T1 mapping in four heartbeats with inline MyoMapNet: a deep learning-based T1 estimation approach

Journal of Cardiovascular Magnetic Resonance, 2022
Purpose To develop and evaluate MyoMapNet, a rapid myocardial T1 mapping approach that uses fully connected neural networks (FCNN) to estimate T1 values from four T1-weighted images collected after a single inversion pulse in four heartbeats (Look-Locker,
Rui Guo, Hossam El-Rewaidy, Salah Assana, Xiaoying Cai, Amine Amyar, Kelvin Chow, Xiaoming Bi, Tuyen Yankama, Julia Cirillo, Patrick Pierce, Beth Goddu, Long Ngo, Reza Nezafat   +12 more
doaj   +1 more source

Clinical evaluation of the Multimapping technique for simultaneous myocardial T1 and T2 mapping

Frontiers in Cardiovascular Medicine, 2022
The Multimapping technique was recently proposed for simultaneous myocardial T1 and T2 mapping. In this study, we evaluate its correlation with clinical reference mapping techniques in patients with a range of cardiovascular diseases (CVDs) and compare ...
Charlotta Jarkman, Carl-Johan Carlhäll, Carl-Johan Carlhäll, Carl-Johan Carlhäll, Markus Henningsson, Markus Henningsson   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

T1 Mapping - Aplicações Cardíacas [PDF]

, 2022
Introdução: A ressonância magnética cardíaca é um método não invasivo de diagnóstico e seguimento das doenças do sistema cardiovascular. Avanços mais recentes permitiram o desenvolvimento da técnica de T1 mapping, que permite identificar pequenas ...
Diogo Plasencia e Quelhas
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts

Translational Oncology, 2016
Human brain tumors such as glioblastomas are typically detected using conventional, nonquantitative magnetic resonance imaging (MRI) techniques, such as T2-weighted and contrast enhanced T1-weighted MRI.
Kelsey Herrmann, Bernadette O. Erokwu, Mette L. Johansen, James P. Basilion, Vikas Gulani, Mark A. Griswold, Chris A. Flask, Susann M. Brady-Kalnay   +7 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

T1- and ECV-mapping in clinical routine at 3 T: differences between MOLLI, ShMOLLI and SASHA

BMC Medical Imaging, 2019
Background T1 mapping sequences such as MOLLI, ShMOLLI and SASHA make use of different technical approaches, bearing strengths and weaknesses. It is well known that obtained T1 relaxation times differ between the sequence techniques as well as between ...
Julius F. Heidenreich, Andreas M. Weng, Julian Donhauser, Andreas Greiser, Kelvin Chow, Peter Nordbeck, Thorsten A. Bley, Herbert Köstler   +7 more
doaj   +1 more source

Improved segmented modified Look-Locker inversion recovery T1 mapping sequence in mice. [PDF]

PLoS ONE, 2017
To develop and evaluate a 2D modified Look-Locker (MOLLI) for high-resolution T1 mapping in mice using a 3T MRI scanner.To allow high-resolution T1 mapping in mice at high heart rates a multi-shot ECG-triggered 2D MOLLI sequence was developed.
Maryam Nezafat, Isabel T Ramos, Markus Henningsson, Andrea Protti, Tamer Basha, René M Botnar, René M Botnar   +6 more
doaj   +1 more source