Results 151 to 159 of about 9,692 (159)
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T6SS: shoot and scrub

Nature Reviews Microbiology, 2020
This study shows that T6SS-mediated killing of competitors is most effective if a lytic toxin is injected.
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A new class of polymorphic T6SS effectors and tethers

2022
AbstractBacteria use the type VI secretion system (T6SS) to deliver toxic effectors into bacterial or eukaryotic cells during interbacterial competition, host colonization, or when resisting predation. The identity of many effectors remains unknown. Here, we identify RIX, a new domain that defines a class of polymorphic T6SS cargo effectors. RIX, which
Katarzyna Kanarek   +3 more
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Refined egoist: The toxin–antitoxin immune system of T6SS

Microbial Pathogenesis
The Type VI secretory system (T6SS) is a key regulatory network in the bacterial system, which plays an important role in host-pathogen interactions and maintains cell homeostasis by regulating the release of effector proteins in specific competition.
Ziduo, Chen   +7 more
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Klebsiella pneumoniae T6SS impact in IBDs

Journal of Crohn's and Colitis
Abstract Background and aims Our hypothesis is that Klebsiella pneumoniae (Kp) Type VI Secretion System (T6SS), normally used for bacteria competition during host colonization have a collateral impact on the host inflammatory pathway (Fig1).
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T6SS-effector hunters uncover PIX: a novel delivery/marker domain

Trends in Microbiology
Gram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raising novel questions in the field.
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T6SS cases its own tail

Nature Reviews Microbiology, 2015
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A duet of T6SS effectors

Cell Host & Microbe
Lingfang Zhu, Xihui Shen
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