Results 1 to 10 of about 6,764,527 (311)

Non-viral transfection technologies for next-generation therapeutic T cell engineering [PDF]

open access: yesBiotechnology Advances, 2021
Genetically engineered T cells have sparked interest in advanced cancer treatment, reaching a milestone in 2017 with two FDA-approvals for CD19-directed chimeric antigen receptor (CAR) T cell therapeutics. It is becoming clear that the next generation of CAR T cell therapies will demand more complex engineering strategies and combinations thereof ...
Raes, Laurens   +3 more
openaire   +2 more sources

T cell fate mapping and lineage tracing technologies probing clonal aspects underlying the generation of CD8 T cell subsets [PDF]

open access: yesScandinavian Journal of Immunology, 2020
AbstractT cells responding to acute infections generally provide two key functions to protect the host: (1) active contribution to pathogen elimination and (2) providing long‐lived cells that are poised to rapidly respond to renewed infection, thus ensuring long‐lasting protection against the particular pathogen.
Shaima Al Khabouri, Carmen Gerlach
openaire   +2 more sources

GBT-CHAIN: A System Framework for Solving the General Trilemma in Permissioned Blockchains

open access: yesDistributed Ledger Technol. Res. Pract., 2023
As a subset of distributed systems, blockchain technology is equally bound by the CAP trilemma. Specifically, no distributed system can satisfy consistency, availability, and partition tolerance simultaneously.
Han Wang   +4 more
semanticscholar   +1 more source

Next-Generation Sequencing Technologies for Early-Stage Cutaneous T-Cell Lymphoma [PDF]

open access: yesFrontiers in Medicine, 2019
The diagnosis of early stage cutaneous T-cell lymphoma is often difficult, particularly in mycosis fungoides (MF), because the clinical presentation, histological findings, and laboratory findings of MF resemble those of inflammatory skin diseases such as atopic dermatitis, psoriasis, and parapsoriasis en plaque.
Kazuyasu Fujii, Takuro Kanekura
openaire   +3 more sources

General Video Coding Technology in Responses to the Joint Call for Proposals on Video Compression With Capability Beyond HEVC

open access: yesIEEE transactions on circuits and systems for video technology (Print), 2020
After the development of the High-Efficiency Video Coding Standard (HEVC), ITU-T VCEG and ISO/IEC MPEG formed the Joint Video Exploration Team (JVET), which started exploring video coding technology with higher coding efficiency, including development of
B. Bross   +10 more
semanticscholar   +1 more source

Older Adults and Smart Technology: Facilitators and Barriers to Use

open access: yesFrontiers of Computer Science, 2022
Smart technologies (e.g., smartphones, smart security technologies, digital home assistants) have advanced over the years and will continue to do so.
M. Harris, Kenneth Blocker, W. Rogers
semanticscholar   +1 more source

Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer [PDF]

open access: yesBriefings in Functional Genomics, 2018
Next-generation sequencing has produced a large quantity of DNA or RNA sequences related to the processes occurring within tumors and their microenvironment in a reasonable time and cost. These data have been used to guide the identification of neoantigens and to determine their specific T-cell receptors.
Qinan, Yin, Jiaxing, Tang, Xuekai, Zhu
openaire   +2 more sources

Information Technology Governance and Bank Performance: A Situational Approach

open access: yesInternational Journal of Financial Studies, 2023
The aim of this paper is to provide empirical evidence about the effect of organizational competition (OC) as a contextual factor on the relationship between the effectiveness of information technology governance (ITG), which informs accounting ...
B. Khamees
semanticscholar   +1 more source

Examining the Relationships between Primary School Students' Participation in Sports and Technology Addictions

open access: yesInternational Journal of Education in Mathematics Science and Technology, 2023
This study aims to determine the relationship between primary school students' technology addiction levels and their participation in sports. For this purpose, in this study, technology addiction and sports participation levels of students studying in ...
Yernar Ospankulov   +6 more
semanticscholar   +1 more source

The impact of digital technology use on adolescent well-being


open access: yesDialogues in Clinical Neuroscience, 2020
This review provides an overview of the literature regarding digital technology use and adolescent well-being. Overall, findings imply that the general effects are on the negative end of the spectrum but very small.
T. Dienlin, Niklas Johannes
semanticscholar   +1 more source

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