Results 191 to 200 of about 13,979,009 (326)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
T-test for two dependent samples - some practical notes
Slovak Journal of Sport ScienceThis paper focuses on some important issues of the t-test for two dependent samples (paired t-test). Emphasis is placed on the assumptions of the use of the test, on the correct formulation of the tested hypotheses and on the selection of the correct ...
Erika Liptáková
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Multivariate Welch t-test on distances. [PDF]
Bioinformatics, 2016 Alekseyenko AV.
europepmc +1 more source
Welch’s t test is more sensitive to real world violations of distributional assumptions than student’s t test but logistic regression is more robust than either [PDF]
David Curtis
openalex +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Development of F-N-C-O Taguchi Method for Robust Measurement System Using a Case Study of T-Peel Test on Adhesion Strength [PDF]
, 2020 Rozzeta Dolah +5 more
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source