Results 61 to 70 of about 106,365 (113)

MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

Oncogenesis, 2017
Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC.
P. Vychytilová-Faltejsková, J. Merhautová, T. Machackova, I. Gutiérrez-García, J. García‐Solano, L. Radová, Dominika Brchnelová, K. Slabá, M. Svoboda, J. Halámková, R. Demlova, I. Kiss, R. Vyzula, P. Conesa‐Zamora, O. Slabý   +14 more
semanticscholar   +1 more source

Development of a Heat Transfer Model for a Free Double Piston and Identification of Thermal Management Challenges

Engineering Proceedings
The Free Double-Piston Composite Cycle Engine (FDP-CCE) integrates the turbofan engine architecture with the characteristics of piston engines with the aim of improving engine efficiency and decreasing CO2 emissions.
Konstantinos Fotis, Zinon Vlahostergios, Dimitrios Misirlis, Kyros Yakinthos   +3 more
doaj   +1 more source

Beyond Mitigation: New Metrics for Space Sustainability Assessment

Engineering Proceedings
The escalating volume of space operations and the proliferation of satellites underscore the urgent need for a pivotal shift towards sustainable space use.
Sara Qaddoumi, Ernestina Cianca, Mauro De Sanctis, Tommaso Rossi, Kathiravan Thangavel, Marina Ruggieri   +5 more
doaj   +1 more source

Installation Effects of Supersonic Inlets on Next-Generation SST Turbofan Engines

Engineering Proceedings
This study explores inlet-related installation effects on next-generation SST aircraft, focusing on supersonic business jets. Using a comprehensive framework with consistent thrust/drag bookkeeping and realistic modeling of inlet losses, including ...
Stylianos Adamidis, Dario Del Gatto, Christos Mourouzidis, Stephen Brown, Vassilios Pachidis   +4 more
doaj   +1 more source

Assessment of the Fatigue Behavior of Wings with Distributed Propulsion

Engineering Proceedings
The integration of distributed electric propulsion into a wing significantly alters the dynamic behavior of the wing. Consequently, the loads on the wing structure in service, in particular upon transient gust and landing impact loads, change ...
Lukas Kettenhofen, Martin Schubert, Kai-Uwe Schröder   +2 more
doaj   +1 more source

E2F1 regulates miR-215-5p to aggravate paraquat-induced pulmonary fibrosis via repressing BMPR2 expression.

Toxicological Research, 2022
Jie Huang, Yan Cao, Xiang Li, Fang Yu, Xiao-jun Han   +4 more
semanticscholar   +1 more source

Numerical Analysis of Potential Energy Recovery via a Thermoelectric Generator (TEG) for the Next-Generation Hybrid-Electric Regional Aircraft

Engineering Proceedings
The thermal management of next-generation hybrid electric regional aircrafts poses critical challenges due to extreme heat loads, which could reach more than 2 MW and must be dissipated.
Safa Sabet, Werner Gumprich, Michael Moeller, Andrés Felgueroso, Iván González Nieves, Miguel Díaz, Simone Mancin   +6 more
doaj   +1 more source

The Development of a Test Stand for Electric Fuel-Cell Turbocharger Integrity Testing—Part 2: Results

Engineering Proceedings
This paper presents the results of a testbench regarding the effects of liquid water content in the turbine stage of a fuel-cell charging system. The testbench simulates the exhaust conditions of a PEM fuel cell to evaluate erosion potential in a single ...
Georgios Karakasis, Sebastian Kunze, Georgios Iosifidis, Anestis Kalfas   +3 more
doaj   +1 more source

How Life Cycle Assessment Supports Sustainability Reporting: Example from Clean Aviation

Engineering Proceedings
The aim of this work is to present how the Life Cycle Assessment (LCA) tool can support sustainability reporting. A comprehensive analysis enables organizations to generate precise and quantitative data, e.g., on resource consumption, thus aligning with ...
Ana Claudia Nioac de Salles, Peter Brantsch   +1 more
doaj   +1 more source

Use of Cabin Sidewall for Thermal Management Applications

Engineering Proceedings
With increased electrification of new aircraft designs, cooling becomes more challenging. The most straightforward solution is to activate yet unused heat sinks available in the aircraft.
Victor Norrefeldt, Gerhard Riedl
doaj   +1 more source