Study on sustainable and resilient supply of medical radioisotopes in the EU [PDF]
This report presents an overview of the current use of radionuclides for medical therapy in Europe as well as an estimate on the amounts being used. It also provides the expert opinion of more than 200 professionals in the field of nuclear medicine and ...
CHITI Arturo +7 more
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Interim analysis of the REASSURE (Radium-223 alpha Emitter Agent in non-intervention Safety Study in mCRPC popUlation for long-teRm Evaluation) study: patient characteristics and safety according to prior use of chemotherapy in routine clinical practice [PDF]
Purpose: REASSURE is a global, prospective, non-interventional study to assess long-term safety of radium-223 in patients with bone metastatic castration-resistant prostate cancer.
Bayh I. +11 more
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Ra-223 dichloride management in a Nuclear Medicine Unit: experience of a referral institution [PDF]
Ra-223 dichloride is a first-in-class alpha-emitting radiopharmaceutical recently introduced into clinical practice for treatment of men with Castration-Resistant Prostate Cancer (CRPC) and symptomatic bone metastases.
Giulia Anna Follacchio* +4 more
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A review of survival analysis methods used in NICE technology appraisals of cancer treatments: consistency, limitations and areas for improvement [PDF]
Objectives: In June 2011, the National Institute for Health and Care Excellence (NICE) Decision Support Unit published a Technical Support Document (TSD) providing recommendations on survival analysis for NICE technology appraisals (TAs).
Ahmed Sowdani +11 more
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Dutch Economic Value of Radium-223 in Metastatic Castration-Resistant Prostate Cancer [PDF]
BACKGROUND: The treatment of metastatic castration-resistant prostate cancer has changed with the introduction of radium-223, cabazitaxel, abiraterone and enzalutamide.
Baka, A +8 more
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A DNA-Encoded Chemical Library Incorporating Elements of Natural Macrocycles [PDF]
Here we show a seven-step chemical synthesis of a DNA-encoded macrocycle library (DEML) on DNA. Inspired by polyketide and mixed peptide-polyketide natural products, the library was designed to incorporate rich backbone diversity.
Gillingham, Dennis +4 more
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Aqueous synthetic methods and their applications in DNA-encoded chemical libraries [PDF]
Water is the basis for all living organisms on Earth and most biochemical processes proceed in aqueous environments. To study biological systems, chemists have developed numerous procedures to perform chemical transformations in the presence of water ...
Stress, Cedric
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Neoolivea tectonae Aime & McTaggart 2020
Neoolivea tectonae (Racib.) Aime & McTaggart, Fungal Syst. Evol. 7: 40 (2020) ≡ Olivea tectonae (Racib.) Thirum., Curr. Sci. 18: 176. 1949. = Olivea tectonae (T.S. Ramakr. & K. Ramakr.) R.L. Mulder, in Mulder and Gibson, C.M.I. Descr. Pathog. Fungi
Aime, M. Catherine +3 more
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Carbonbeton unter Hochtemperaturbeanspruchung [PDF]
Thematisch befasse ich mich in meiner Dissertation mit der experimentellen Untersuchung von Carbonbeton unter Hochtemperaturbeanspruchung. Um die Thematik grundlegend aufzuarbeiten, wurden zuerst die Prüfmöglichkeiten zur Bestimmung der Zug- und ...
Holz, Karoline
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The Evolution of Diet Width in Lasioglossum (Chilalictus) (Halictidae, Apoidea), in Association with Speciation and Sensory Morphology [PDF]
Bees are highly dependent on flowers as a source of food, from which they collect oil, nectar or pollen. While most bees rely on multiple plants for nectar, some species specialize on specific pollen hosts while other are generalists.
Akankunda, Trace
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