Results 1 to 10 of about 19 (17)

Treatment patterns and health outcomes in metastatic renal cell carcinoma patients treated with targeted systemic therapies in the UK. [PDF]

BMC Cancer, 2020
Funder: Bristol Myers Squibb Pharmaceuticals Ltd.Abstract: Background: Patients with metastatic renal cell carcinoma (mRCC) treated with targeted systemic therapies have demonstrated favourable outcomes in randomised controlled trials, however real-world
Hawkins R, Fife K, Hurst M, Wang M, Naicker N, Nolasco S, Eisen T, Matakidou A, Gordon J.   +8 more
europepmc   +6 more sources

Incremental benefits of novel pharmaceuticals in the UK: a cross-sectional analysis of NICE technology appraisals from 2010 to 2020. [PDF]

BMJ Open, 2022
Polak TB, Cucchi DGJ, Darrow JJ, Versteegh MM.   +3 more
europepmc   +1 more source

Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway. [PDF]

J Biol Chem, 2014
Cohen A, Kupiec M, Weisman R.
europepmc   +1 more source

Centralisation of specialist cancer surgery services in two areas of England: the RESPECT-21 mixed-methods evaluation [PDF]

, 2023
Background: Centralising specialist cancer surgical services is an example of major system change. High-volume centres are recommended to improve specialist cancer surgery care and outcomes.
Barod, Ravi, Bex, Axel, Bhuiya, Afsana, Black, Georgia, Boaden, Ruth, Brinton, Veronica, Clarke, Caroline S, Fahy, Patrick, Fulop, Naomi J, Hines, John, Hunter, Rachael, Levermore, Claire, Maddineni, Satish, Melnychuk, Mariya, Morris, Steve, Mughal, Muntzer M, Ng, Pei Li, Perry, Catherine, Pritchard-Jones, Kathy, Ramsay, Angus IG, Sandell, John, Shackley, David, Tran, Maxine, Vallejo-Torres, Laura, Vindrola-Padros, Cecilia, Wood, Victoria J   +25 more
core   +4 more sources

Cave shrimps Troglocaris s. str. (Dormitzer, 1853), taxonomic revision and description of new taxa after phylogenetic and morphometric studies [PDF]

, 2012
FIGURE 1. Distribution map of eight taxa of the subgenus Troglocaris s. str., with phylogroup/subgroup designation (in brackets, as in Zakšek et al. 2009).
Jalžić, Branko, Jugovic, Jure, Prevorčnik, Simona, Sket, Boris   +3 more
core   +2 more sources

Polyphenols as Morphogenetic Agents for the Controlled Synthesis of Mesoporous Silica Nanoparticles [PDF]

, 2019
Non-surfactant-induced synthesis of mesoporous silica nanoparticles (MSNPs) is gaining increasing interest because of their low toxicity and simple purification compared to conventional surfactant-based methods.
Boesel, LF, Luo, J, Osypova, A, Panzarasa, G, Rossi, RM, Sadeghpour, A, Sorin, F, Spano, F   +7 more
core   +2 more sources

Aqueous synthetic methods and their applications in DNA-encoded chemical libraries [PDF]

, 2019
Water is the basis for all living organisms on Earth and most biochemical processes proceed in aqueous environments. To study biological systems, chemists have developed numerous procedures to perform chemical transformations in the presence of water ...
Stress, Cedric
core   +1 more source

Разработка технологического процесса изготовления детали «Опора» [PDF]

, 2017
Объектом исследования является "опора". Цель работы - решение задача по созданию эффективного технологического процесса изготовления детали. В данном работе, проектировен процесс изготовления детали.The object of research is "support." The purpose of the
Сюй Хэ
core  

Treatments for renal cell carcinoma: NICE Pilot Treatment Pathways Appraisal [PDF]

Background The National Institute for Health and Care Excellence is piloting a new approach to evaluating health technologies, which takes into consideration the full treatment pathway for a condition.
Abdelsabour, A., Ahmad, Z., Barnish, M.S., Brand, A., Burns, D., Coelho, H., Crathorne, L., Farmer, C., Lee, D., Lovell, A., Matthews, J., Melendez-Torres, G.J., Muthukumar, M., Nikoglou, T., O’Toole, B., Robinson, S., Snowsill, T.M., Trigg, L.A., Wilson, E.C.F.   +18 more
core   +1 more source

Lenvatinib plus pembrolizumab for untreated advanced renal cell carcinoma:a systematic review and cost-effectiveness analysis [PDF]

BACKGROUND: Renal cell carcinoma is the most common type of kidney cancer, comprising approximately 85% of all renal malignancies. Patients with advanced renal cell carcinoma are the focus of this National Institute for Health and Care Excellence ...
Beale, Sophie, Bhattacharyya, Devarshi, Boland, Angela, Chaplin, Marty, Chow, Shien, Edwards, Katherine, Fleeman, Nigel, Greenhalgh, Janette, Houten, Rachel, Maden, Michelle, Mahon, James, McEntee, Joanne, Nevitt, Sarah, Waddell, Tom   +13 more
core   +2 more sources