Treatment patterns and health outcomes in metastatic renal cell carcinoma patients treated with targeted systemic therapies in the UK. [PDF]
Funder: Bristol Myers Squibb Pharmaceuticals Ltd.Abstract: Background: Patients with metastatic renal cell carcinoma (mRCC) treated with targeted systemic therapies have demonstrated favourable outcomes in randomised controlled trials, however real-world
Hawkins R +8 more
europepmc +6 more sources
Centralisation of specialist cancer surgery services in two areas of England: the RESPECT-21 mixed-methods evaluation [PDF]
Background: Centralising specialist cancer surgical services is an example of major system change. High-volume centres are recommended to improve specialist cancer surgery care and outcomes.
Barod, Ravi +25 more
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Cave shrimps Troglocaris s. str. (Dormitzer, 1853), taxonomic revision and description of new taxa after phylogenetic and morphometric studies [PDF]
FIGURE 1. Distribution map of eight taxa of the subgenus Troglocaris s. str., with phylogroup/subgroup designation (in brackets, as in Zakšek et al. 2009).
Jalžić, Branko +3 more
core +2 more sources
Polyphenols as Morphogenetic Agents for the Controlled Synthesis of Mesoporous Silica Nanoparticles [PDF]
Non-surfactant-induced synthesis of mesoporous silica nanoparticles (MSNPs) is gaining increasing interest because of their low toxicity and simple purification compared to conventional surfactant-based methods.
Boesel, LF +7 more
core +2 more sources
Aqueous synthetic methods and their applications in DNA-encoded chemical libraries [PDF]
Water is the basis for all living organisms on Earth and most biochemical processes proceed in aqueous environments. To study biological systems, chemists have developed numerous procedures to perform chemical transformations in the presence of water ...
Stress, Cedric
core +1 more source
Разработка технологического процесса изготовления детали «Опора» [PDF]
Объектом исследования является "опора". Цель работы - решение задача по созданию эффективного технологического процесса изготовления детали. В данном работе, проектировен процесс изготовления детали.The object of research is "support." The purpose of the
Сюй Хэ
core
Treatments for renal cell carcinoma: NICE Pilot Treatment Pathways Appraisal [PDF]
Background The National Institute for Health and Care Excellence is piloting a new approach to evaluating health technologies, which takes into consideration the full treatment pathway for a condition.
Abdelsabour, A. +18 more
core +1 more source
Lenvatinib plus pembrolizumab for untreated advanced renal cell carcinoma:a systematic review and cost-effectiveness analysis [PDF]
BACKGROUND: Renal cell carcinoma is the most common type of kidney cancer, comprising approximately 85% of all renal malignancies. Patients with advanced renal cell carcinoma are the focus of this National Institute for Health and Care Excellence ...
Beale, Sophie +13 more
core +2 more sources
Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer:The STAR non-inferiority RCT [PDF]
BackgroundThere is interest in using treatment breaks in oncology, to reduce toxicity without compromising efficacy. Trial designA Phase II/III multicentre, open-label, parallel-group, randomised controlled non-inferiority trial assessing treatment ...
core +1 more source
Dictamen Preliminar de Evaluación de Tecnología Sanitaria N° 048-SDEPFYOTS-DETS-IETSI-2019. Eficacia y seguridad de nivolumab en combinación con ipilimumab para el tratamiento de pacientes adultos con cáncer renal metastásico de células claras de pronóstico intermedio y pobre, sin tratamiento sistémico previo [PDF]
En este documento se plasma la evaluación de la eficacia y seguridad del uso del producto farmacéutico nivolumab en combinación con ipilimumab en pacientes adultos con cáncer renal metastásico de células claras de pronóstico intermedio y pobre, sin ...
Burela Prado, Paula Alejandra +4 more
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