Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network. [PDF]
Stat Methods Med Res, 2022 BACKGROUND: Synthesis of clinical effectiveness from multiple trials is a well-established component of decision-making. Time-to-event outcomes are often synthesised using the Cox proportional hazards model assuming a constant hazard ratio over time ...
Freeman SC +5 more
europepmc +4 more sources
Trends in NICE technology appraisals of non-small cell lung cancer drugs over the last decade. [PDF]
Eur J Health EconOBJECTIVES: The aim of this study is to analyse the trends in technology appraisals for non-small cell lung cancer (NSCLC) treatments performed by the National Institute for Health and Care Excellence (NICE) over the last ten years.METHODS: A systematic ...
Westerink L +6 more
europepmc +3 more sources
Cost-effectiveness analysis of atezolizumab in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen: a United Kingdom health care perspective [PDF]
, 2023 BackgroundCost-effectiveness of atezolizumab, as a treatment for advanced non-small-cell lung cancer (NSCLC) patients who cannot receive a platinum-containing regimen,was still unknown. Our objective was to evaluate the cost-effectiveness of atezolizumab
Jiaqi Li +6 more
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Precision Oncology and Cancer Biomarkers [PDF]
, 2022 This open access book reflects on matters of social and ethical concern raised in the daily practices of those working in and around precision oncology. Each chapter addresses the experiences, concerns and issues at stake for people who work in settings ...
core +4 more sources
Broadening health technology assessment:To support setting boundaries to the basic benefit package [PDF]
, 2023 The content of the basic benefit package is restricted by evaluating the costs and benefits of healthcare interventions. Decision-making frameworks based on health technology assessment (HTA) have been developed to support this process.
Enzing, Joost
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Observation of Antinormally Ordered Hanbury-Brown--Twiss Correlations [PDF]
, 2004 We have measured antinormally ordered Hanbury-Brown--Twiss correlations for coherent states of electromagnetic field by using stimulated parametric down-conversion process.
Akihisa Tomita +7 more
core +1 more source
Aerobic power, huddling and the efficiency of torpor in the South American marsupial, Dromiciops gliroides. [PDF]
, 2012 During periods of cold, small endotherms depend on a continuous supply of food and energy to maintain euthermic body temperature (T(b)), which can be challenging if food is limited. In these conditions, energy-saving strategies are critical to reduce the
Chappell, Mark A +5 more
core +3 more sources
Cave shrimps Troglocaris s. str. (Dormitzer, 1853), taxonomic revision and description of new taxa after phylogenetic and morphometric studies [PDF]
, 2012 FIGURE 1. Distribution map of eight taxa of the subgenus Troglocaris s. str., with phylogroup/subgroup designation (in brackets, as in Zakšek et al. 2009).
Jalžić, Branko +3 more
core +2 more sources
A systematic review of economic evaluations assessing the cost-effectiveness of licensed drugs used for previously treated epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) negative advanced/metastatic non-small cell lung cancer [PDF]
, 2019 Background Non-small cell lung cancer (NSCLC) is one of the most commonly diagnosed cancers. There are many published studies of cost-effectiveness analyses of licensed treatments, but no study has compared these studies or their approaches ...
Armoiry, Xavier +4 more
core +1 more source
Modelling Health State Utilities as a Transformation of Time to Death in Patients with Non-Small Cell Lung Cancer [PDF]
, 2023 Background: When utilities are analyzed by time to death (TTD), this has historically been implemented by ‘grouping’ observations as discrete time periods to create health state utilities.
Chaudhary, Mohammad A +7 more
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