Results 161 to 170 of about 7,324,140 (348)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi   +5 more
wiley   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Using Exclusive Web Crawlers to Store Better Results in Search Engines' Database [PDF]

open access: yesInternational Journal of Web & Semantic Technology Vol.4, No.2, April 2013, 2013
Crawler-based search engines are the mostly used search engines among web and Internet users, involve web crawling, storing in database, ranking, indexing and displaying to the user. But it is noteworthy that because of increasing changes in web sites search engines suffer high time and transfers costs which are consumed to investigate the existence of
arxiv  

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Ekstraksi Tabel HTML ke Database Management System dengan Pendekatan Service Oriented Architecture

open access: yesJurnal Komputer Terapan, 2017
Seiring dengan perkembangan berbagai bisnis proses, keberadaan data yang ada semakin berkembang dalam berbagai bentuk. Salah satu bentuk data adalah tabel di dalam sebuah halaman HTML. Berbeda dengan tabel pada database, tabel HTML memiliki struktur yang
Memen Akbar, Ardianto Wibowo
doaj  

On the effects of logical database design on database size, query complexity, query performance, and energy consumption [PDF]

open access: yesarXiv
Database normalization theory is the basis for logical design of relational databases. Normalization reduces data redundancy and consequently eliminates potential data anomalies, while increasing the computational cost of read operations. Despite decades worth of applications of normalization theory, it still remains largely unclear to what extent ...
arxiv  

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

New Approach To Traffic Density Estimation Based On Indoor And Outdoor Scenes From CCTV

open access: yesFoundations of Computing and Decision Sciences, 2015
In this paper we present an algorithm for precise estimation of moving objects density (typically people and vehicles) in indoor and outdoor scenes. Automatic generation of the so-called density maps is based on video sequences acquired by surveillance ...
Chmielewska Agata   +3 more
doaj   +1 more source

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