Results 61 to 70 of about 7,492,517 (328)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

A Novel Database Acceleration Technology for Full Table Scans

open access: yesIEEE Access
Advancements in hardware technology, especially Field Programmable Gate Arrays (FPGAs), have shown potential in enhancing database performance. Yet, much of the existing research has neglected crucial aspects such as the database-hardware interface and ...
Chuang Zhang, Xuebin Tang, Yuanxi Peng
doaj   +1 more source

Performance comparison between Xamarin and Java database operations

open access: yesJournal of Computer Sciences Institute, 2018
Work with database is one of base things in developing an application. Every technology/language uses own ways to work with database. In the case of Android the SQLite relational database management system is used.
Oleh Datsko, Elżbieta Miłosz
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

MBGD update 2018: microbial genome database based on hierarchical orthology relations covering closely related and distantly related comparisons

open access: yesNucleic Acids Res., 2018
The Microbial Genome Database for Comparative Analysis (MBGD) is a database for comparative genomics based on comprehensive orthology analysis of bacteria, archaea and unicellular eukaryotes. MBGD now contains 6318 genomes.
I. Uchiyama   +4 more
semanticscholar   +1 more source

Exoplanet Orbit Database. II. Updates to Exoplanets.org [PDF]

open access: yes, 2014
The Exoplanet Orbit Database (EOD) compiles orbital, transit, host star, and other parameters of robustly-detected exoplanets reported in the peer-reviewed literature.
E. Han   +6 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Funding Sources for Key Water Quality Strategies, Craig, M [PDF]

open access: yes, 2004
The New Hampshire Estuaries Project (NHEP) Management Plan, published in 2000, sets forth three goals related to estuarine water quality in the State’s coastal watershed, and twenty Water Quality Action Plans to implement these goals.
Craig, Matt
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

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