Results 81 to 90 of about 7,492,517 (328)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

AN EFFICIENT DATA MINING METHOD TO FIND FREQUENT ITEM SETS IN LARGE DATABASE USING TR- FCTM [PDF]

open access: yesICTACT Journal on Soft Computing, 2016
Mining association rules in large database is one of most popular data mining techniques for business decision makers. Discovering frequent item set is the core process in association rule mining.
Saravanan Suba, T. Christopher
doaj  

MpBsmi: A new algorithm for the recognition of continuous biological sequence pattern based on index structure. [PDF]

open access: yesPLoS ONE, 2018
A significant approach for the discovery of biological regulatory rules of genes, protein and their inheritance relationships is the extraction of meaningful patterns from biological sequence data.
Weina Li, Jiadong Ren
doaj   +1 more source

Microsatellite primers for red drum (Sciaenops ocellatus) [PDF]

open access: yes, 2008
In this note, we document polymerase-chain-reaction (PCR) primer pairs for 101 nuclear-encoded microsatellites designed and developed from a genomic library for red drum (Sciaenops ocellatus).
Gold, John R.   +3 more
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

From ternary relationship to relational tables: a case against common beliefs [PDF]

open access: yes, 2002
The transformation from n-ary relationships to a relational database schema has never been really fully analyzed. This paper presents one of the several ternary cases ignored by the ER-to-RM literature.
Camps Pare, Rafael
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

PELACAKAN KEMBALI KONTROL-KONTROL OBYEK PADA PENAMBAHAN OBYEK SECARA DINAMIS BERBASIS VISUAL BASIC STUDI KASUS ANALISA HIRARKI TUGAS

open access: yesJUTI: Jurnal Ilmiah Teknologi Informasi, 2003
Pembentukan HTA(Hierarchical Task Analysis) pada dunia nyata dapat menentukan urutan tugas yang harus diselesaikan dan beberapa jalan / cara yang dapat dicapai baik secara horizontal maupun vertikal.
Dwi Sunaryono
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

PropBase QueryLayer : a single portal to UK physical property databases (extended abstract) [PDF]

open access: yes, 2010
As the host institution of the National Geoscience Data Centre (NGDC), the British Geological Survey (BGS) holds significant volumes of subsurface data on behalf of the UK.
Holmes, Keith   +3 more
core  

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