Results 61 to 70 of about 7,018,255 (270)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Table of content [PDF]

, 2013
Eric Swankoski, George Mason, Kanwalinderjit Kaur Gagneja, Vashek Matyáš, Rakesh Verma   +4 more
  +10 more sources

Front Cover, Publication Information [PDF]

, 2009
Front Cover, Publication Information, Table of ...

core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Spis treści

Zeszyty Teoretyczne Rachunkowości, 2014
Od Zespołu Redakcyjnego ............................................................................... 5 Mieczysław Dobija – Rachunkowość w systemie pomiaru aktywności ekonomicznej państwa – Accounting as part of an economic activity measurement ...
Mieczysław Dobija, Ewelina Puchalska, Dawid Wróblewski   +2 more
doaj  

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Table of content [PDF]

, 2014
Giuseppe Thadeu Freitas de Abreu, Siamak Yousefi, Xiao-Wen Chang, Behailu Y. Shikur, Reza Monir Vaghefi, Virginia Tech, R. Michael Buehrer, Arghavan Amini, Jorge Robles, Gregory Cardenas-Mansilla, Yuan Yang, Y. B. Zhao, Robert Piché, Asim Bilajbegović, Frank Stephan, Jens Einsiedler, Yang Liu, Marzieh Dashti, Zhang Jie, Benjamin Wagner, Nicolas Amiot, Emanuel Staudinger, Stephan Adler, Simon Schmitt, Panayiotis Kolios, Ali Golestani, Fraunhofer Esk, Neda Petreska, Dennis Wilfert, Abdo Gaber, Ali M. Alsaih, A. H. Omar, Marcus Ehrig, Ihp Gmbh, Markus Petri, Jesús Gutiérrez Terán, Ben Moez, Alexandre Raymond, Patrick Henkel, Julian Lategahn, Marcel Tkocz, Octavi Font, Anders Jönsson, Phil Bartie, William Mackaness   +44 more
  +12 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Bacterial contamination of table eggs and the influence of housing systems [PDF]

, 2008
With the introduction of alternative housing systems for laying hens in the EU, recent research has focussed on the bacterial contamination of table eggs, e.g. eggshell and egg content contamination.
Herman, L., Heyndrickx, M., Messens, W., Reu, K., de, Rodenburg, T.B., Uyttendaele, M.   +5 more
core   +2 more sources