Results 101 to 110 of about 505,708 (364)

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner   +12 more
wiley   +1 more source

Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing

open access: yesBMJ Paediatrics Open, 2018
Objectives Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially unavailable 10 mg tablets, with functional break lines, are split commonly in an attempt to deliver the correct ...
Jude Madathilethu   +5 more
semanticscholar   +1 more source

Effectiveness of a Telephone‐Delivered Walk With Ease Program on Arthritis‐Related Symptoms, Function, and Activity: A Randomized Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini   +5 more
wiley   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

open access: yesAdvanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter   +3 more
wiley   +1 more source

Learning with mobile devices: A comparison of four mobile learning pilots in Africa

open access: yesSouth African Journal of Education, 2019
This paper compares the mixed-methods evaluation findings of the ukuFUNda Virtual School (UVS) with evaluations of three different mobile learning (m-learning) programmes in Africa: the information and communication technologies for rural education ...
Shafika Isaacs   +2 more
doaj   +1 more source

Swallowing a cellular automaton pill: predicting drug release from a matrix tablet [PDF]

open access: yesSimulation, 90:227-237 (2014), 2012
Matrix tablets are drug delivery devices designed to release a drug in a controlled manner over an extended period of time. We develop a cellular automaton (CA) model for the dissolution and release of a water-soluble drug and excipient from a matrix tablet of water-insoluble polymer.
arxiv  

Cladribine Tablets: A Review in Relapsing MS

open access: yesCNS Drugs, 2018
Cladribine is a deoxyadenosine analogue prodrug that preferentially depletes lymphocytes, key cells underlying multiple sclerosis (MS) pathogenesis. Cladribine tablets (Mavenclad®) represent the first short-course oral disease-modifying drug (DMD) for ...
E. Deeks
semanticscholar   +1 more source

TABLET IN TABLET: A REVIEW [PDF]

open access: yesAsian Journal of Research in Chemistry and Pharmaceutical Sciences, 2020
D Nandal   +2 more
openaire   +1 more source

Paracetamol Syrup: A Paradigm Shift in Post-immunisation Fever Management [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Dear Editor, The Universal Immunisation Programme (UIP) in India was launched in 1978 by the Government of India in collaboration with the World Health Organisation (WHO). The main objective of the programme is to provide free vaccination services to
R Akhil, Deepu Palal
doaj   +1 more source

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

open access: yesAdvanced Engineering Materials, EarlyView.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng   +7 more
wiley   +1 more source

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