Results 81 to 90 of about 125,081 (296)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Scientific photography and experimental activities: didactic books of chemistry

open access: yesACTIO: Docência em Ciências, 2018
Photography is a non-verbal language that contributes to the exposition of theoretical research, artistic-cultural manifestations and as an effective adjunct in numerous scientific-technological discoveries.
Catherine Flor Geraldi Vogt   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Structure of the Interstellar Medium of Star Forming Galaxies [PDF]

open access: yes, 2012
We present numerical methods for including stellar feedback in galaxy-scale simulations. We include heating by SNe (I & II), gas recycling and shock-heating from O-star & AGB winds, HII photoionization, and radiation pressure from stellar photons.
Audit   +96 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Moisture-tolerant resin-based sealant: A boon

open access: yesContemporary Clinical Dentistry, 2013
Background and Objectives: Pit and fissure sealants are highly effective in preventing occlusal caries. The present study clinically evaluated and compared the retention and development of caries when sealed with moisture-tolerant resin-based sealant ...
Prasanna Kumar Bhat   +3 more
doaj   +1 more source

Embedded-Cluster Calculations in a Numeric Atomic Orbital Density-Functional Theory Framework [PDF]

open access: yes, 2014
We integrate the all-electron electronic structure code FHI-aims into the general ChemShell package for solid-state embedding (QM/MM) calculations. A major undertaking in this integration is the implementation of pseudopotential functionality into FHI ...
Ahlrichs R.   +11 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Low Temperature Oxidation of Cyclohexane: Uncertainty of Important Thermo-Chemical Properties

open access: yesEurasian Chemico-Technological Journal, 2018
The study of the standard formation enthalpy, entropy, and heat capacity for key species relevant to the low-temperature combustion of cyclohexane has been performed by applying the group additivity method of Benson. The properties of 18 Benson groups (8
M. Abbasi, N. Slavinskay, U. Riedel
doaj   +1 more source

Scattering length of the ground state Mg+Mg collision [PDF]

open access: yes, 2001
We have constructed the X 1SIGMAg+ potential for the collision between two ground state Mg atoms and analyzed the effect of uncertainties in the shape of the potential on scattering properties at ultra-cold temperatures.
B. Liu   +40 more
core   +3 more sources

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